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首页> 外文期刊>American Journal of Drug Discovery and Development >Role of C-Peptide in Development of Diabetic Neuropathy [DN] Animal Model
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Role of C-Peptide in Development of Diabetic Neuropathy [DN] Animal Model

机译：C肽在糖尿病性神经病[DN]动物模型发展中的作用

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摘要

Diabetes is an increasingly common disorder which causes and contributes to a variety of complications which are often associated with neuropathic condition. Diabetic neuropathy is a group of disorders and as such the most common chronic complication affecting both type1 and type 2 diabetic patients. Diabetic research in preclinical studies has emerged as a promising area in the recent times. The current models used in the study for understanding diabetic complications are not efficient enough for producing reliable results about neuropathy. The role of C-peptide in development of neuropathy is clear and can be used as a tool to study neuropathy and even the molecular pathways can be studied by using it. Here with the help of collected data it is concluded that DN model could be developed with the help of C-peptide which may be used as standard model in diabetic neuropathy.
机译：糖尿病是一种越来越常见的疾病，其引起并导致多种并发症，这些并发症通常与神经性疾病有关。糖尿病性神经病是一组疾病，因此影响1型和2型糖尿病患者的最常见的慢性并发症。临床前研究中的糖尿病研究近来已成为有希望的领域。该研究中用于理解糖尿病并发症的当前模型不足以产生关于神经病的可靠结果。 C肽在神经病发展中的作用是明确的，可以用作研究神经病的工具，甚至可以使用它来研究分子途径。在此借助于收集的数据得出结论，可以借助于C肽开发DN模型，所述C肽可以用作糖尿病性神经病的标准模型。

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