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Oocyte related factors impacting on embryo quality: relevance for in vitro embryo production

机译：卵母细胞相关因素影响胚胎质量：与体外胚胎生产的相关性

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摘要

The outcome of pregnancy is closely linked to early events that occur during the onset of embryogenesis. The first stages in embryonic development are mainly governed by the storage of maternal factors present in the oocyte at the time of fertilisation. In this review, we outline the different classes of oocyte transcripts that may be involved in activation of the embryonic genome as well as those associated with epigenetic reprogramming, imprinting maintenance or the control of transposon mobilisation during preimplantation development. We also report the influence of cumulus-oocyte crosstalk during the maturation process on the oocyte transcriptome and how in vitro procedures can affect these interactions.
机译：怀孕的结果与胚胎发生过程中发生的早期事件密切相关。胚胎发育的第一阶段主要由受精时卵母细胞中母体因子的储存决定。在这篇综述中，我们概述了可能参与胚胎基因组激活以及与表观遗传重编程，印迹维持或在植入前发育过程中控制转座子动员有关的卵母转录物的不同类别。我们还报告了卵母细胞转录组成熟过程中卵卵母细胞串扰的影响以及体外程序如何影响这些相互作用。

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