Phylogenetic Considerations in the Evolutionary Development of Aminoglycoside Resistance Genes in Pathogenic Bacteria

Tommy Rodriguez

首页> 外文期刊>Annual Research & Review in Biology >Phylogenetic Considerations in the Evolutionary Development of Aminoglycoside Resistance Genes in Pathogenic Bacteria

【24h】

Phylogenetic Considerations in the Evolutionary Development of Aminoglycoside Resistance Genes in Pathogenic Bacteria

机译：病原细菌中氨基糖苷抗性基因进化发展中的系统发育考虑。

获取原文

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

This study revisits antibiotic resistance as a source of evolutionary development in pathogenic bacteria. By taking a molecular phylogenetic approach to this inquiry, I seek to find homologous correlations in antimicrobial resistance gene families across a broad spectrum of bacteria, as to identify the possible acquisition of those genes through divergent events in evolutionary context. In order to test this, I examine the various degrees of genetic similarity in two antimicrobial resistance genomic datasets, namely aadA1 & aadA2 aminoglycoside resistance genes, among bacteria that occur in a multitude of environments. Moreover, the results from phylogenetic analysis suggests that pathogenic antibiotic resistance for aadA1 & aadA2 aminoglycoside resistance genes may have been acquired through evolutionary events with a common ancestor of a soil-dwelling bacterium.

机译：这项研究将抗生素抗性作为病原细菌进化发展的一个来源。通过采取一种分子系统发育方法，我寻求在广泛的细菌谱中找到抗菌素耐药基因家族的同源相关性，以通过进化背景下的发散事件来识别这些基因的可能获取。为了测试这一点，我检查了在多种环境中发生的细菌之间两个抗菌素抗性基因组数据集，即aadA1和aadA2氨基糖苷抗性基因的不同程度的遗传相似性。此外，系统发育分析的结果表明，aadA1和aadA2氨基糖苷抗性基因的致病性抗生素抗性可能是通过与土壤细菌共同祖先发生的进化事件获得的。

著录项

来源
《Annual Research & Review in Biology》 |2015年第2期|共8页
作者
Tommy Rodriguez;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种
中图分类普通生物学;
关键词

相似文献

外文文献
中文文献
专利

1. Genomic evidence for antibiotic resistance genes of actinomycetes as origins of antibiotic resistance genes in pathogenic bacteria simply because actinomycetes are more ancestral than pathogenic bacteria. [J] . Woo PC, Lau SK, Huang Y, Medical hypotheses . 2006,第6期

机译：放线菌的抗生素抗性基因是致病菌中抗生素抗性基因的起源的基因组证据，仅仅是因为放线菌比致病菌更祖传。
2. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria [J] . Macmaster Rachel, Zelinskaya Natalia, Savic Miloje, Nucleic Acids Research . 2010,第21期

机译：产生抗生素和人类病原菌对氨基糖苷抗性A1408 16S rRNA甲基转移酶功能的结构洞察
3. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria [J] . C. Robert Rankin, Graeme L. Conn, Miloje Savic, Nucleic acids research . 2010,第21期

机译：产生抗生素和人类致病菌对氨基糖苷抗性A1408 16S rRNA甲基转移酶功能的结构洞察
4. Phylogenetic Analysis of Four Vibrio Strains of Pathogenic Bacteria Based on Hemolysin Genes and 16S rRNA Genes [C] . Xiuli Wang, Ye Yuan, Hongyue Wang, Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009 . 2009

机译：基于溶血素基因和16S rRNA基因的四种病原菌弧菌菌株的系统发育分析
5. Morphology, embryonic development and ultrastructure as a consideration for phylogenetic analysis of Cephalobina, Rhabditina, Diplogastrina and Tylenchida (Secernentea: Nemata). [D] . Dolinski, Claudia de Melo. 1999

机译：形态，胚胎发育和超微结构是对头足类，Rhabditina，Diplogastrina和Tylenchida（Secernentea：Nemata）进行系统发育分析的考虑。
6. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria [O] . Rachel Macmaster, Natalia Zelinskaya, Miloje Savic, 2010

机译：产生抗生素和人类致病菌对氨基糖苷抗性A1408 16S rRNA甲基转移酶功能的结构洞察
7. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria [O] . Macmaster, Rachel, Zelinskaya, Natalia, Savic, Miloje, 2010

机译：产生抗生素和人类致病菌对氨基糖苷抗性A1408 16S rRNA甲基转移酶功能的结构洞察
8. Aminoglycoside Resistance: Structure, Occurrence, and Identification of Genes Encoding Aminoglycoside-Modifying Enzymes [R] . Vliegenthart, J. S. 1991

机译：氨基糖苷类抗药性：氨基糖苷类修饰酶基因的结构，发生和鉴定

Phylogenetic Considerations in the Evolutionary Development of Aminoglycoside Resistance Genes in Pathogenic Bacteria

摘要

著录项

相似文献

相关主题

期刊订阅