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Elettaria cardamomum seed mediated rapid synthesis of gold nanoparticles and its biological activities

机译:种子介导的金纳米粒子的快速合成及其生物活性

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Plant mediated synthesis of metal nanoparticles has drawn the attention of researchers due to their unique features and extensive application in various fields. The present report is on the unexploited environmentally benign rapid synthesis of gold nanoparticles of size 15.2nm using the aqueous extract of Elettaria cardamomum seeds. Studies on antioxidant, antibacterial and anticancer activities of the nanoparticles have been carried out. The invitro radical scavenging activity of the biogenic nanogold is found to be comparable to that of the reference. The as synthesized gold nanoparticles also exhibits antibacterial activity against a broad spectrum of bacterial pathogens. The antibacterial activity is found to be enhanced against S.aureus compared to E.coli and P.aeruginosa . Further, the obtained nanoparticles show excellent cytotoxic activity towards HeLa cancer cell lines. Graphical abstract Display Omitted Highlights ? Elettaria cardamomum seed extract mediated synthesis of gold nanoparticles. ? XRD and SAED pattern shows the crystallinity of GNPs. ? The obtained GNPs exhibits potent antioxidant and antibacterial activity. ? Excellent cytotoxic effect of gold nanoparticle has been observed in HeLa cell lines.
机译:植物介导的金属纳米颗粒的合成因其独特的功能和在各个领域的广泛应用而吸引了研究人员的注意。本报告是关于使用小豆蔻(Elettaria cardamomum)种子的水提物未开发的对环境有益的快速合成大小为15.2nm的金纳米颗粒的方法。已经对纳米颗粒的抗氧化剂,抗菌和抗癌活性进行了研究。发现该生物纳米金的体外自由基清除活性与参照物相当。合成的金纳米颗粒还表现出对广谱细菌病原体的抗菌活性。与大肠杆菌和铜绿假单胞菌相比,发现对金黄色葡萄球菌的抗菌活性增强。此外,所获得的纳米颗粒对HeLa癌细胞系显示出优异的细胞毒性活性。图形摘要显示省略的突出显示?小豆蔻种子提取物介导的金纳米颗粒的合成。 ? XRD和SAED图显示了GNP的结晶度。 ?获得的GNP显示出有效的抗氧化剂和抗菌活性。 ?在HeLa细胞系中已观察到金纳米粒子具有出色的细胞毒性作用。

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