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Dual properties of Nigella Sativa: Anti-oxidant and Pro-oxidant

机译:苜蓿的双重特性:抗氧化剂和促氧化剂

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Nigella sativa (NS) or black seed has been used for the treatment of various disorders for centuries. Experimentally, seed extract or thymoquinone (TQ) which is the main constituent of its oil has been reported to have anti-inflammatory, antineoplastic and anticancer properties. Interestingly, the published data demonstrates that NS acts as anti-oxidant in various diseases simultaneously, it behaves like a pro-oxidant for cancer cells. Here, we have summarized the dual properties of this medicinal plant. Current review is systematic, based on search from PubMed. Pubmed data indicated that NS has both anti-oxidant and pro-oxidant properties in different cell types hence should be used carefully because it acts as a cytoprotective or cytotoxic agent in inflammatory and malignant conditions respectively.
机译:百日草(Nigella sativa,NS)或黑种子已用于治疗各种疾病。根据实验,种子提取物或作为其油主要成分的胸腺醌(TQ)具有抗炎,抗肿瘤和抗癌的特性。有趣的是,已发表的数据表明,NS在多种疾病中同时起着抗氧化剂的作用,就像癌细胞的抗氧化剂一样。在这里,我们总结了这种药用植物的双重特性。根据PubMed的搜索,当前的评论是系统的。公开数据表明,NS在不同细胞类型中均具有抗氧化剂和促氧化剂特性,因此应谨慎使用,因为它分别在炎性和恶性条件下充当细胞保护剂或细胞毒剂。

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