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首页> 外文期刊>Archives of Biological Sciences >ANTI-INFLAMMATORY POTENTIAL OF DIFFERENT EXTRACTS ISOLATED FROM THE ROOTS OF Ficus lacor Buch . Hum and Murraya koenigii L. Spren g
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ANTI-INFLAMMATORY POTENTIAL OF DIFFERENT EXTRACTS ISOLATED FROM THE ROOTS OF Ficus lacor Buch . Hum and Murraya koenigii L. Spren g

机译：榕根提取物不同提取物的抗炎作用。嗡嗡声和Murraya koenigii L.Spren g

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The present study was undertaken to evaluate the anti-inflammatory potential of Murraya koenigii root extracts petroleum ether, ethyl acetate and chloroform (MKPE , MKEA and MKCF, respectively) and Ficus lacor aerial root extracts petroleum ether, ethyl acetate, chloroform and ethanol (FLPE , FLET, FLCF and FLET, respectively) at doses of 50 and 100 mg/kg body weight (b.w.) using animal models of acute inflammation (carrageenan-, histamine- and serotonin-induced inflammation). The results of the Murraya koenigii roots chloroform extract caused 66.4% inhibition and the ethanol extract of Ficus lacor aerial roots caused 68.3% inhibition at the dose of 50 mg/kg b.w. At a higher dose of 100 mg/kg b.w., MKPE and MKCF showed 55.10% and 70.10% inhibition, respectively. FLPE and FLET showed 74.50% and 75.40% inhibition, respectively, in the carrageenan-induced inflammation model. In histamine-induced inflammation, the MKCF showed 60% inhibition, and 67.01% and 68.02% inhibition with the petroleum ether and ethanol extracts, respectively, in Ficus lacor aerial roots at the dose of 50 mg/kg b.w. At a higher dose (100 mg/kg b.w.), MKCF showed 64% inhibition. FLPE and FLET showed 70.13%and 74.01% inhibition, respectively; 62.15% and 66.10% inhibition was observed with the petroleum ether and ethanol extracts of Ficus lacor aerial roots at 50 mg/kg b.w. At higher dose (100 mg/kg b.w.), FLPE and FLET showed 69.10% and 68.72% inhibition in serotonin-induced inflammation.
机译：进行本研究以评估墨角兰根提取物石油醚，乙酸乙酯和氯仿（分别为MKPE，MKEA和MKCF）和无花果榕根提取物的石油醚，乙酸乙酯，氯仿和乙醇（FLPE）的抗炎潜力使用急性炎症（角叉菜胶，组胺和5-羟色胺诱发的炎症）动物模型，分别以50和100 mg / kg体重（bw）的剂量服用FLET，FLET，FLCF和FLET）。剂量为50 mg / kg b.w时，Murraya koenigii根的氯仿提取物抑制66.4％，而榕榕气根的乙醇提取物抑制68.3％。在100 mg / kg b.w.的较高剂量下，MKPE和MKCF分别显示出55.10％和70.10％的抑制作用。在角叉菜胶诱导的炎症模型中，FLPE和FLET分别显示出74.50％和75.40％的抑制作用。在组胺诱导的炎症中，榕树根气生根在剂量为50 mg / kg b.w时，用石油醚和乙醇提取物分别抑制MKCF的60％，67.01％和68.02％。在较高剂量（100 mg / kg b.w.）下，MKCF表现出64％的抑制作用。 FLPE和FLET分别显示出70.13％和74.01％的抑制率;用50 mg / kg b.w.的榕叶榕气生根的石油醚和乙醇提取物观察到抑制率为62.15％和66.10％。在较高剂量（100 mg / kg b.w.）下，FLPE和FLET对5-羟色胺诱导的炎症表现出69.10％和68.72％的抑制作用。

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