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Chronic epididymitis and Grade III varicocele and their associations with semen characteristics in men consulting for couple infertility

机译:慢性不育症和III级精索静脉曲张及其与精液特征的关系,男性咨询夫妇不育症

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Chronic epididymitis and varicocele are frequently observed genital disorders in men consulting for couple infertility, but their impact on semen characteristics at the time of infertility consultation is still a matter of debate. We investigated 652 male partners of couples who had their first infertility consultation between 1999 and 2015 in Argentina. Men with chronic epididymitis (n = 253), Grade III varicocele (n = 106), and both conditions (n = 125) were compared with a control group (n = 168) composed of men without these disorders or any other recognized causes of male infertility. We showed that men who presented isolated chronic epididymitis were more likely to have high percentages of low sperm motility and abnormal sperm morphology as well as a high number of white blood cells. Men with isolated Grade III varicocele had low sperm production and motility and an increased percentage of abnormal sperm morphology. Finally, men who simultaneously presented chronic epididymitis with Grade III varicocele had a low sperm motility and increased percentage of abnormal sperm morphology as well as a high number of white blood cells. Physical examination of the genital organs may identify common disorders, potentially involved as causal factors of patient's infertility. These disorders are associated with specific seminal profiles that should help in identifying the best treatment from the available therapeutic options, effectiveness, safety, and allowing as much as possible natural conception.
机译:慢性附睾炎和精索静脉曲张经常在男性咨询夫妇不育症的生殖器疾病中观察到,但是在不育咨询时它们对精液特征的影响仍是一个争论的问题。我们调查了652对夫妇的男性伴侣,这些伴侣在1999年至2015年间在阿根廷进行了首次不孕症咨询。将患有慢性附睾炎(n = 253),三级精索静脉曲张(n = 106)和两种情况(n = 125)的男性与对照组(n = 168)进行比较,该对照组由无这些疾病或任何其他公认的原因引起的男性组成男性不育。我们发现表现出孤立的慢性附睾炎的男性更有可能具有较高百分比的低精子运动力和异常精子形态以及大量白细胞。患有三级精索静脉曲张的男性精子产生量和运动能力低下,并且精子形态异常的百分比增加。最后,同时伴有Ⅲ级精索静脉曲张的慢性附睾炎的男性精子活动力低,精子形态异常的百分比增加,白细胞增多。生殖器官的体格检查可以确定常见的疾病,可能是患者不孕症的致病因素。这些疾病与特定的精液特征有关,应有助于从可用的治疗选择,有效性,安全性以及尽可能多的自然观念中识别最佳治疗方法。

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