Multifunctional neural probe integrated with push–pull microfluidic channels and microelectrode and biosensors for real-time monitoring of neurochemicals with neural spikes

Uikyu Chae; Hyogeun Shin; Il-Joo Cho

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Multifunctional neural probe integrated with push–pull microfluidic channels and microelectrode and biosensors for real-time monitoring of neurochemicals with neural spikes

机译：集成了推挽式微流体通道，微电极和生物传感器的多功能神经探针，可实时监测带有神经尖峰的神经化学物质

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We designed and tested a few variants of Bongwoori in the transmembrane segment of the VSD to disrupt the dimerization of the VSD. Improving our ability to control this dimerization will lead to better Forster Resonance Energy Transfer GEVIs for in vivo imaging.

机译：我们在VSD的跨膜部分设计并测试了Bongwoori的几种变体，以破坏VSD的二聚化。改善我们控制这种二聚化的能力将为体内成像带来更好的Forster共振能量转移GEVI。

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《IBRO Reports》 |2019年第1期|共2页
作者
Uikyu Chae; Hyogeun Shin; Il-Joo Cho;
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中图分类神经病学与精神病学;
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1. Fabrication of flexible microelectrode arrays integrated with microfluidic channels for stable neural interfaces [J] . Gao K., Li G., Liao L., Sensors and Actuators, A. Physical . 2013,第Null期

机译：集成了微流体通道的柔性微电极阵列的制备，用于稳定的神经接口
2. Parylene flexible neural probes integrated with microfluidic channels [J] . Shoji Takeuchi, D.Ziegler, Y.Yoshida, Lab on a chip . 2005,第5期

机译：聚对二甲苯柔性神经探针与微流体通道集成
3. Biosensor microprobes with integrated microfluidic channels for bi-directional neurochemical interaction [J] . O Frey, P D van der Wal, S Spieth, Journal of neural engineering . 2011,第6期

机译：具有集成微流体通道的生物传感器微探针，用于双向神经化学相互作用
4. A new MEMS neural probe system integrated with push-pull microfluidic channels and biosensors for real-time monitoring of neurochemicals [C] . Uikyu Chae, Hyoguen Shin, Hyunjoo Jenny Lee, IEEE International Conference on Micro Electro Mechanical Systems . 2016

机译：集成了推挽微流体通道和生物传感器的新型MEMS神经探针系统，用于实时监测神经化学物质
5. Neural Biosensor Probes for Simultaneous Electrophysiological Recordings, Neurochemical Measurements, and Drug Delivery with High Spatial and Temporal Resolution. [D] . Gibson, Matthew Donivan. 2011

机译：用于同时电生理记录，神经化学测量和高时空分辨率药物输送的神经生物传感器探头。
6. High-density microelectrode array recordings and real-time spike sorting for closed-loop experiments: an emerging technology to study neural plasticity [O] . Felix Franke, David Jäckel, Jelena Dragas, 2012

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8. Optical Performance Monitoring of PSK Data Channels Using Artificial Neural Networks Trained with Parameters Derived from Delay-Tap Asynchronous Diagrams via Balanced Detection. [R] . Wu, X., Jargon, J. A., Jia, Z., 2009

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Multifunctional neural probe integrated with push–pull microfluidic channels and microelectrode and biosensors for real-time monitoring of neurochemicals with neural spikes

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