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首页> 外文期刊>Ibnosina Journal of Medicine and Biomedical Sciences >Bacteria Etiological Agents Causing Lower Respiratory Tract infections at Western Part of Nepal
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Bacteria Etiological Agents Causing Lower Respiratory Tract infections at Western Part of Nepal

机译：尼泊尔西部地区引起下呼吸道感染的细菌病原体

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Objectives: Lower respiratory tract infections (LRTIs) are among the most common infectious disease. This study focused on determining the bacterial etiology of LRTIs among the patients attending Nepalgunj Medical College & teaching Hospital, Banke, in western Nepal. Materials and Methods: A prospective study conducted on 426 specimens, received from patients with suspected LRTIs attending out-patients and in-patients departments. The specimens were collected and processed according to standard methodology in the Central Laboratory of Microbiology at Nepalgunj Medical College and Teaching Hospital, Banke, Nepal between the periods of January 2012 to December 2012.Results: Respiratory pathogens were recovered from 49.3% cases (n=210). Bacteria were more commonly recovered from endotracheal (ET) secretion (86, 41%) than in sputum (82, 39%) and bronchial washing (42, 20%). 80% (n=168) growth was monomicrobial while the rest accounted for mixed growth. Gram‐negative bacteria were in 80.9% (n=246) and gram-positive bacteria were 19.1% (n=58). Among the Gram-positive organisms isolated, Streptococcus pneumoniae (30, 51.7%) was the most predominant pathogen followed by Staphylococcus aureus (28, 48.3%) and in Gram-negative organisms isolated, Pseudomonas aeruginosa (116,47.2%) was most predominant pathogen followed by Haemophilus influenzae (68, 27.6%) Klebsiella pneumoniae (36, 14.6%), Escherichia coli (26, 10.6%). Conclusions: P. aeruginosa and S. pnemoniae were the most common gram negative and gram-positive bacterial isolates recovered, respectively from LRTIs urging for monitoring and surveillance of these pathogens. Key words: Bacteria etiological agent, Lower Respiratory tract infections, Respiratory aspirates, Nepal.
机译：目的：下呼吸道感染（LRTIs）是最常见的传染病之一。这项研究的重点是确定在尼泊尔西部班克的Nepalgunj医学院和教学医院就诊的患者中LRTIs的细菌病因。材料和方法：对来自门诊和住院部门的疑似LRTI患者的426个样本进行了前瞻性研究。从2012年1月至2012年12月，在尼泊尔班基的Nepalgunj医学院和教学医院的微生物学中央实验室按照标准方法对标本进行了收集和处理。结果：从49.3％的病例中回收了呼吸道病原体（n = 210）。从气管内（ET）分泌物中回收细菌的比例更高（86％，41％），而在痰液中（82％，39％）和支气管冲洗液中的细菌（42％，20％）更为常见。 80％（n = 168）的增长是单微生物的，其余的则是混合增长的。革兰氏阴性菌占80.9％（n = 246），革兰氏阳性菌占19.1％（n = 58）。在分离的革兰氏阳性菌中，肺炎链球菌（30，51.7％）是最主要的病原体，其次是金黄色葡萄球菌（28，48.3％），在分离的革兰氏阴性菌中，铜绿假单胞菌（116,47.2％）是最主要的病原体。病原体，其次是流感嗜血杆菌（68，27.6％），肺炎克雷伯菌（36，14.6％），大肠杆菌（26，10.6％）。结论：铜绿假单胞菌和肺炎链球菌分别是从LRTI中回收的最常见的革兰氏阴性和革兰氏阳性细菌分离株，敦促监测和监测这些病原体。关键词：细菌病原体，下呼吸道感染，呼吸道抽吸物，尼泊尔。

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