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首页> 外文期刊>Ibnosina Journal of Medicine and Biomedical Sciences >Colchicine Poisoning: A Case of Deliberate Self Poisoning, Late Presentation and Fatal Outcome
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Colchicine Poisoning: A Case of Deliberate Self Poisoning, Late Presentation and Fatal Outcome

机译:秋水仙碱中毒:故意自毒,迟发和致命结果

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Colchicine poisoning is relatively uncommon, but potentially life threatening event due to the high toxicity of the drug and ability to precipitate severe multi-organ failure in overdose. Colchicine is used primarily in the treatment of acute attacks of gout and inflammatory diseases. We report a the first case of a 18 -year-old Libyan female who presented to the emergency department approximately 20-28 hours after ingesting 30 mg of colchicine in a suicide attempt. In spite of gastric lavage, use of activated charcoal and supportive measures, multi-organ system failure developed over the following two days, and patient died on the third day after admission. Salient toxicological and clinical aspects of colchicine poisoning are discussed. Keywords: Colchicine, Toxicity, Death, Poisoning
机译:秋水仙碱中毒相对少见,但由于药物的高毒性和用药过量导致严重的多器官衰竭的能力,可能会危及生命。秋水仙碱主要用于治疗痛风和炎症性疾病的急性发作。我们报告了第一例18岁的利比亚女性,她在服用30毫克秋水仙碱自杀企图后约20-28小时出现在急诊科。尽管洗胃,使用活性炭和辅助措施,在接下来的两天内仍出现多器官系统衰竭,患者在入院后第三天死亡。秋水仙碱中毒的主要毒理学和临床方面进行了讨论。关键词:秋水仙碱,毒性,死亡,中毒

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