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首页> 外文期刊>Indian heart journal >Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI
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Association of syntax score with short-term outcomes among acute ST-elevation myocardial infarction patients undergoing primary PCI

机译:接受原发性PCI的急性ST段抬高型心肌梗死患者语法评分与近期预后的关系

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Objective: Syntax score (SX) has emerged as a reproducible angiographic tool to quantify the extent of coronary artery disease based on location and complexity of each lesion. It has been shown to predict long-term clinical outcomes in patients with left main or multi-vessel disease and recently also in ST-segment elevation myocardial infarction undergoing primary PCI. The aim of this study was to evaluate whether the syntax score is associated with short-term cardiovascular outcomes in patients treated with primary percutaneous coronary intervention (PCI) for acute ST-segment elevation myocardial infarction (STEMI). Methods: Syntax score was determined in 90 consecutive patients (mean age 54.2+/-11.6) of STEMI undergoing primary PCI. Outcomes were stratified according to syntax score groups: SX low @?15 (n=33), SX mid 16-22 (n=30), and SX high >=23 (n=27). The primary endpoint was all-cause mortality at 30 days. Secondary endpoints were nonfatal major adverse cardiac and cerebrovascular events (MACE) defined as a composite of any repeat revascularization, acute coronary syndrome, and stroke at 30 days in patients discharged alive. Results: Mortality at 30 days was higher in the SX high group compared to the SX mid and SX low group (18.5% vs 3.3% p=0.011), MACE at 30 days was higher in SX high group compared to SX mid and SX low group (48.1% vs 16.6% vs 9.1%, p=0.001). Conclusions: The syntax score is associated with 30-day mortality in patients with STEMI undergoing primary PCI. In those discharged, it is associated with risk of MACE at 30 days.
机译:目的:语法评分(SX)已成为一种可重现的血管造影工具,可根据每个病变的位置和复杂性来量化冠状动脉疾病的程度。已经显示出可以预测左主干或多支血管疾病患者的长期临床结果,最近还可以预测接受原发性PCI的ST段抬高型心肌梗塞的患者。这项研究的目的是评估在急性ST段抬高型心肌梗死(STEMI)的经皮冠状动脉介入治疗(PCI)患者中,语法评分是否与短期心血管疾病预后相关。方法:在连续90例STEMI接受原发性PCI的患者(平均年龄54.2 +/- 11.6)中确定语法评分。根据语法评分组对结果进行分层:SX低@ 15(n = 33),SX中16-22(n = 30)和SX高> = 23(n = 27)。主要终点是30天时的全因死亡率。次要终点是非致命性重大心脏和脑血管不良事件(MACE),定义为活着患者在30天时重复进行的血运重建,急性冠脉综合征和中风的综合。结果:SX高组的30天死亡率高于SX中和SX低组(18.5%vs 3.3%p = 0.011),SX高组30天MACE高于SX中和SX低组组(48.1%vs. 16.6%vs 9.1%,p = 0.001)。结论:语法评分与接受原发性PCI的STEMI患者30天死亡率有关。在出院的患者中,其与30天时发生MACE的风险有关。

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