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Psychiatric morbidity in asymptomatic human immunodeficiency virus patients

机译:无症状人类免疫缺陷病毒患者的精神病发病率

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Background:Psychiatric morbidity in human immunodeficiency virus (HIV) patients is being studied all over the world. There is paucity of Indian literature particularly in asymptomatic HIV individuals.Aim:The aim of the following study is to establish the prevalence and the determinants of psychiatric morbidity in asymptomatic HIV patients.Materials and Methods:A cross-sectional study was undertaken to assess psychiatric morbidity as per ICD-10 dacryocystorhinostomy criteria in 100 consecutive asymptomatic seropositive HIV patients and an equal number of age, sex, education, economic and marital status matched HIV seronegative control. All subjects were assessed with the general health questionnaire (GHQ), mini mental status examination, hospital anxiety and depression scale (HADS) and sensation seeking scale (SSS) and the scores were analyzed statistically.Results:Asymptomatic HIV positive patients had significantly higher GHQ caseness and depression but not anxiety on HADS as compared to HIV seronegative controls. On SSS asymptomatic HIV seropositive subjects showed significant higher scores in thrill and adventure seeking, experience seeking and boredom susceptibility as compared to controls. HIV seropositive patients had significantly higher incidence of total psychiatric morbidity. Among the individual disorders, alcohol dependence syndrome, sexual dysfunction and adjustment disorder were significantly increased compared with HIV seronegative controls.Conclusion:Psychiatric morbidity is higher in asymptomatic HIV patients when compared to HIV seronegative controls. Among the individual disorders, alcohol dependence syndrome, sexual dysfunction and adjustment disorder were significantly increased compared with HIV seronegative controls. High sensation seeking and substance abuse found in HIV seropositive patients may play a vital role in engaging in high-risk behavior resulting in this dreaded illness.
机译:背景:人类免疫缺陷病毒(HIV)患者的精神疾病发病率正在世界范围内研究。目的:以下研究的目的是确定无症状HIV患者的精神病患病率和决定因素。材料与方法:进行横断面研究以评估精神病学根据ICD-10泪囊鼻腔吻合术标准,在100例连续无症状血清阳性HIV患者中发病,并且年龄,性别,教育程度,经济和婚姻状况相同的人数与HIV血清阴性对照相匹配。结果:无症状HIV阳性患者GHQ明显升高,所有患者均进行了一般健康状况调查表(GHQ),简易精神状况检查,医院焦虑抑郁量表(HADS)和感觉寻求量表(SSS)的评估。与艾滋病毒血清阴性对照相比,对HADS的案例分析和抑郁分析没有焦虑。在SSS上,无症状的HIV血清阳性受试者与对照组相比,在寻求刺激和冒险,寻求经验和无聊易感性方面得分更高。 HIV血清阳性患者的总精神病发病率显着更高。在个体疾病中,酒精依赖综合征,性功能障碍和适应障碍与艾滋病毒血清阴性对照相比明显增加。结论:无症状艾滋病毒患者的精神病发病率高于艾滋病毒血清阴性对照。在个体疾病中,与HIV血清阴性对照相比,酒精依赖综合征,性功能障碍和适应障碍明显增加。在HIV血清反应阳性患者中寻求高感觉和滥用药物可能在导致这种可怕疾病的高风险行为中起着至关重要的作用。

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