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首页> 外文期刊>International Journal of Environmental Research and Public Health >Hepatitis B Vaccination among 1999–2017 Birth Cohorts in Zhejiang Province: The Determinants Associated with Infant Coverage
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Hepatitis B Vaccination among 1999–2017 Birth Cohorts in Zhejiang Province: The Determinants Associated with Infant Coverage

机译：1999-2017年浙江省出生人群的乙肝疫苗接种：与婴儿覆盖率相关的决定因素

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This study aimed to investigate the coverage of hepatitis B vaccine (Hep B) and its completeness and timeliness for birth cohorts from 1999 to 2017 in Zhejiang province, East China. Demographic characteristics and vaccination records of Hep B of children born from 1 January 1999 to 31 June 2017 were extracted from the Zhejiang provincial immunization information system. The timeliness of the first dose of Hep B (Hep B1) was defined as the proportion of children who received the Hep B1 within 24 h after birth among the target population. The completeness of Hep B was defined as the proportion of children who completed the three-dose series of Hep B before 7 years of age. The demographic characteristics of the target population were described. The coverage of each dose of Hep B, the timeliness of Hep B1, and the completeness of Hep B for each birth cohort were described. A logistic regression model was applied to detect the determinants of the timeliness of Hep B1 and the completeness of Hep B vaccination. The coverage of Hep B1 increased from 90.3% to 98.3%, the coverage of Hep B2 increased from 88.8% to 96.1%, and the coverage of Hep B3 increased from 86.4% to 94.2%. The timeliness of Hep B1 increased from 80.3% to 91.3%. The completeness of Hep B increased from 81.3% to 91.5%. The determinants of timeliness of Hep B1 included children’s delivery place, immigration status, maternal education level, and economic development level of resident area. The determinants of completeness of Hep B included children’s delivery place, immigration status, maternal education level, economic development level of resident area, maternal occupation, and frequency of vaccination service. Zhejiang province had achieved significant improvements in the timely administration of Hep B1 and the completeness of Hep B. To accelerate progress toward additional reductions in the transmission of hepatitis B virus, further efforts need to be focused on improving the timeliness of Hep B1 vaccination and reducing the drop-outs among disadvantaged children with the risk factors identified in this study.
机译：本研究旨在调查1999年至2017年中国东部浙江省乙肝疫苗（Hep B）的覆盖率及其出生队列的完整性和及时性。从浙江省免疫信息系统中提取了1999年1月1日至2017年6月31日出生的儿童Hep B的人口统计学特征和疫苗接种记录。乙肝第一剂（乙肝B1）的及时性定义为目标人群中出生后24小时内接受乙肝B1患儿的比例。乙肝的完整性定义为在7岁之前完成三剂乙肝系列的儿童比例。描述了目标人群的人口统计学特征。描述了每个出生人群的每剂乙肝剂量的覆盖率，乙肝的及时性以及乙肝的完整性。应用逻辑回归模型检测Hep B1及时性和Hep B疫苗接种的完整性的决定因素。 Hep B1的覆盖率从90.3％增加到98.3％，Hep B2的覆盖率从88.8％增加到96.1％，Hep B3的覆盖率从86.4％增加到94.2％。 Hep B1的及时性从80.3％增加到91.3％。乙肝的完整性从81.3％增加到91.5％。乙型肝炎B1及时性的决定因素包括儿童的分娩地点，移民状况，孕产妇教育水平以及居民区的经济发展水平。乙肝的完整性决定因素包括孩子的分娩地点，移民状况，母亲的教育水平，居民区的经济发展水平，母亲的职业以及接种疫苗的频率。浙江省在乙肝乙肝的及时管理和乙肝完整性方面取得了显着改善。为加快进一步减少乙肝病毒传播的进程，需要进一步努力提高乙肝乙肝疫苗的及时性和减少在这项研究中确定的具有危险因素的弱势儿童中的辍学率。

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