首页> 外文期刊>International Journal of Environmental Research and Public Health >Association between Heavy Metals, Bisphenol A, Volatile Organic Compounds and Phthalates and Metabolic Syndrome
【24h】

Association between Heavy Metals, Bisphenol A, Volatile Organic Compounds and Phthalates and Metabolic Syndrome

机译:重金属,双酚A,挥发性有机化合物和邻苯二甲酸酯与代谢综合征之间的关联

获取原文
           

摘要

The incidence of metabolic syndrome (MetS), which causes heart disease and stroke, has increased significantly worldwide. Although many studies have revealed the relationship between heavy metals (cadmium, mercury, and lead), the sum of metabolites of di(2-ethylhexyl) phthalate (DEHP), and MetS, the results remain inconsistent. No study has reported the association between various volatile organic compounds (VOCs) and phthalate metabolites with MetS. This cross-sectional study of a representative sample of adult South Koreans aimed to evaluate the relationship between heavy metals, VOC metabolites, phthalate metabolites, bisphenol A and MetS after adjusting for demographic variables. Data from the Korean National Environmental Health Survey II (2012–2014) ( n = 5251) were used in the analysis. Multiple logistic regression analysis was performed for MetS with log-transformed hazardous material quartiles after covariate adjustment. Urine muconic acid (MuA) and mono- (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) levels were significantly associated with MetS after adjusting for confounders (odds ratio: 1.34 and 1.39, respectively). Urine MuA and MEHHP levels were significantly associated with MetS. Because of the rarity of this study, which investigated the relationship between each VOC and phthalate metabolite with MetS and the strict definition of all indirect measures of MetS components, further research is needed.
机译:在世界范围内,引起心脏病和中风的代谢综合征(MetS)的发病率显着增加。尽管许多研究揭示了重金属(镉,汞和铅),邻苯二甲酸二(2-乙基己基)酯(DEHP)和MetS的代谢物之间的关系,但结果仍然不一致。尚无研究报道各种挥发性有机化合物(VOC)与邻苯二甲酸酯代谢物与MetS的关联。这项针对韩国成年人口代表性样本的横断面研究旨在在调整了人口统计学变量后评估重金属,VOC代谢物,邻苯二甲酸酯代谢物,双酚A和MetS之间的关系。分析中使用了第二次韩国国家环境健康调查(2012-2014)的数据(n = 5251)。在协变量调整后,对具有对数转换后的危险物质四分位数的MetS进行多元logistic回归分析。调整混杂因素后,尿粘康酸(MuA)和邻苯二甲酸单-(2-乙基-5-羟基己基)酯(MEHHP)水平与MetS显着相关(比值分别为1.34和1.39)。尿中的MuA和MEHHP水平与MetS显着相关。由于这项研究的稀缺性,该研究调查了每种挥发性有机化合物和邻苯二甲酸酯代谢物与MetS之间的关系,以及对所有间接测量MetS成分的严格定义,因此需要进一步研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号