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首页> 外文期刊>International Journal of Environmental Research and Public Health >Indoor Exposure and Adverse Birth Outcomes Related to Fetal Growth, Miscarriage and Prematurity—A Systematic Review
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Indoor Exposure and Adverse Birth Outcomes Related to Fetal Growth, Miscarriage and Prematurity—A Systematic Review

机译：与胎儿生长，流产和早产有关的室内暴露和不良出生结局—系统评价

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The purpose of this review was to summarize existing epidemiological evidence of the association between quantitative estimates of indoor air pollution and all-day personal exposure with adverse birth outcomes including fetal growth, prematurity and miscarriage. We carried out a systematic literature search of MEDLINE and EMBASE databases with the aim of summarizing and evaluating the results of peer-reviewed epidemiological studies undertaken in “westernized” countries that have assessed indoor air pollution and all-day personal exposure with specific quantitative methods. This comprehensive literature search identified 16 independent studies which were deemed relevant for further review and two additional studies were added through searching the reference lists of all included studies. Two reviewers independently and critically appraised all eligible articles using the Critical Appraisal Skills Programme (CASP) tool. Of the 18 selected studies, 14 adopted a prospective cohort design, three were case-controls and one was a retrospective cohort study. In terms of pollutants of interest, seven studies assessed exposure to electro-magnetic fields, four studies assessed exposure to polycyclic aromatic hydrocarbons, four studies assessed PM2.5 exposure and three studies assessed benzene, phthalates and noise exposure respectively. Furthermore, 12 studies examined infant growth as the main birth outcome of interest, six examined spontaneous abortion and three studies assessed gestational age at birth and preterm delivery. This survey demonstrates that there is insufficient research on the possible association of indoor exposure and early life effects and that further research is needed.
机译：这篇综述的目的是总结现有的流行病学证据，证明室内空气污染定量评估与全天个人暴露与不良出生结局（包括胎儿生长，早产和流产）之间的关联。我们对MEDLINE和EMBASE数据库进行了系统的文献检索，目​​的是总结和评估在“西方国家”进行的同行评审流行病学研究的结果，这些研究已使用特定的定量方法评估了室内空气污染和全天个人暴露。这项全面的文献检索确定了16项独立的研究，这些研究被认为与进一步审查相关，并且通过搜索所有纳入研究的参考文献清单增加了另外两项研究。两名审稿人使用“关键评估技能计划”（CASP）工具独立且严格地评估了所有合格文章。在18项入选的研究中，有14项采用了前瞻性队列设计，三项是病例对照，一项是回顾性队列研究。就感兴趣的污染物而言，七项研究评估了电磁场的暴露，四项研究评估了多环芳烃的暴露，四项研究评估了PM2.5暴露，三项研究评估了苯，邻苯二甲酸酯和噪声暴露。此外，有12项研究将婴儿的成长作为主要的出生结果，6项研究了自然流产，3项研究评估了出生时的胎龄和早产。这项调查表明，关于室内暴露与早期生活影响之间可能存在的关联的研究不足，需要进一步研究。

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