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Improvement of HbA1c and stable weight loss 2 years after an outpatient treatment and teaching program for patients with type 2 diabetes without insulin therapy based on urine glucose self-monitoring

机译:门诊治疗和教学计划实施后2年无尿胰岛素自我监测的无胰岛素治疗的2型糖尿病患者的HbA1c改善和稳定的体重减轻

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Objective: Long-term outcomes after participation in a structured diabetes treatment and teaching program (DTTP) for patients with diabetes without insulin use, primarily based upon postprandial urine glucose self-monitoring (UGSM).Methods: A total of 126 patients took part in the DTTP in a university outpatient department in 2004–2005. We re-evaluated 119 (94.4%) at baseline and at 6 months, 12 months, and 24 months. Hemoglobin A1c (HbA1c) was DCCT adjusted.Results: HbA1c decreased significantly 6 months after education from 7.33% (±1.59%) to 6.89% (±0.98%; P = 0.001 versus baseline) and was maintained for up to 12 months (7.02% ± 1.07%; P = 0.017 versus baseline) as well as up to 24 months (6.96% ± 1.06%; P = 0.005 versus baseline). Weight decreased from 92.5 kg at baseline to 90.3 kg at 24 months (P = 0.014). A total of 36.5% of patients not on insulin therapy preferred UGSM, whereas 23.5% preferred blood glucose monitoring, at 24 months. Glucose control was similar in both groups at 24 months (HbA1c UGSM 7.03 versus blood glucose monitoring 6.97%; P = 0.807).Conclusion: Participation in the DTTP resulted in long-term behavior modification. HbA1c of patients without insulin met the target 24 months after the DTTP, irrespective of the type of glucose self-monitoring.
机译:目的:主要基于餐后尿液葡萄糖自我监测(UGSM),针对未使用胰岛素的糖尿病患者参加结构化糖尿病治疗和教学计划(DTTP)后的长期结果。方法:总共126例患者参加了2004-2005年在大学门诊部的DTTP。在基线,6个月,12个月和24个月时,我们重新评估了119(94.4%)。结果:教育后6个月,HbA1c显着下降,从7.33%(±1.59%)降至6.89%(±0.98%; P = 0.001,相对于基线),并维持了12个月(7.02) %±1.07%;相对于基准,P = 0.017)以及长达24个月(6.96%±1.06%;相对于基准,P = 0.005)。体重从基线的92.5千克减少到24个月的90.3千克(P = 0.014)。未接受胰岛素治疗的患者中,有36.5%的患者在24个月时偏爱UGSM,而23.5%的患者偏爱血糖监测。两组在24个月时的血糖控制相似(HbA1c UGSM 7.03与血糖监测6.97%; P = 0.807)。结论:参与DTTP导致长期行为改变。无血糖患者的HbA1c符合DTTP后24个月的目标,而与血糖自我监测的类型无关。

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