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首页> 外文期刊>Infectious diseases in obstetrics and gynecology >Prevalence of Sexually Transmitted Infections (Neisseria gonorrhoeae,Chlamydia trachomatis,Trichomonasvaginalisand Human Papillomavirus) in Female Attendees of aSexually Transmitted Diseases Clinic in Ulaanbaatar, Mongolia
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Prevalence of Sexually Transmitted Infections (Neisseria gonorrhoeae,Chlamydia trachomatis,Trichomonasvaginalisand Human Papillomavirus) in Female Attendees of aSexually Transmitted Diseases Clinic in Ulaanbaatar, Mongolia

机译：在蒙古乌兰巴托的性传播疾病诊所的女性参与者中发生性传播感染（淋病奈瑟氏球菌，沙眼衣原体，沙眼衣原体和人类乳头瘤病毒）

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Background:Epidemiological data suggest that the prevalence of syphilis, gonorrhea and trichomoniasis hasincreased in both urban and rural areas of Mongolia. These data are primarily substantiated by notifications of casesof clinically apparent disease in both rural and urban areas, plus laboratory diagnoses from the AIDS/STD ReferenceCenter,Ulaanbaatar. In the past 5 years, however, there has been a marked decline in the total number of patientsbeing screened for sexually transmitted infections (STIs). An assessment of true prevalence of STIs in a femalepopulation attending an urban sexually transmitted diseases (STD) clinic was therefore commenced.Methods:Consecutivewomen attending an STD clinic in Ulaanbaatar had genital samples collected by the insertionand immediate removal of a tampon, which was then tested for the presence ofNeisseria gonorrhoeae,Chlamydia trachomatis, human papillomavirus (HPV) andTrichomonas vaginalis, using polymerase chain reaction(PCR) amplification.Results:A total of 110 women were studied (mean age 26.7 years). Overall, 58 (53%) patients had one or morepathogens identified; 43 (39%) had a single pathogen, while 15 (14%) had mixed pathogens.C. trachomatiswasfound in 15 (14%),N. gonorrhoeaein 12 (11%),T. vaginalisin nine (8%) and HPV in 39 (36%). Among the 39HPV-positive patients, oncogenic genotypes (16, 18, 31, 33, 35, 39, 45, 51, 52) were found in 17 (44%) patients.Conclusions:Sexually transmitted infections as defined by PCR were common, and found in 53%of femaleattendees of an urban STD clinic in Mongolia. As infections with conventional STIs increase the risk of humanimmunodeficiency virus (HIV) transmission, it is imperative that strategies be introduced to reduce the prevalenceof STIs. Furthermore, detection of oncogenic HPV was common, indicating that it is vital that a strategy to reducecervical cancer such as a pre-cancer cervical cytology screening program also be introduced.
机译：背景：流行病学数据表明，蒙古城市和农村地区梅毒，淋病和滴虫病的患病率均有上升。这些数据主要通过通知农村和城市地区出现临床明显疾病的病例以及来自乌兰巴托的艾滋病/性病参考中心的实验室诊断来证实。但是，在过去的5年中，接受性传播感染（STIs）筛查的患者总数显着下降。因此，开始对在城市性传播疾病（STD）诊所的女性人群中性传播感染的真实患病率进行评估。通过聚合酶链反应（PCR）扩增检测淋病奈瑟氏球菌，沙眼衣原体，人乳头瘤病毒（HPV）和阴道毛滴虫。结果：总共研究了110名妇女（平均年龄26.7岁）。总体而言，有58名患者（53％）患有一种或多种病原体。 43个（39％）具有单一病原体，而15个（14％）具有混合病原体。沙眼衣原体发现于15（14％），N。淋球菌素12（11％），T。阴道粘蛋白9个（8％），HPV 39个（36％）。在39例HPV阳性患者中，有17例（44％）患者发现了致癌基因型（16、18、31、33、35、39、45、51、52）。结论：PCR定义的性传播感染是常见的，在蒙古城市性病诊所的53％的女性就诊者中发现了这种疾病。随着常规性传播感染的感染增加了人类免疫缺陷病毒（HIV）传播的风险，因此必须采取降低性传播感染发生率的策略。此外，致癌HPV的检测很普遍，这表明至关重要的是，还必须引入减少宫颈癌的策略，例如癌前宫颈细胞学筛查程序。

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