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首页> 外文期刊>International Journal of Research in Medical Sciences >Clinico-pathological study of skin appendageal tumours from northern India
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Clinico-pathological study of skin appendageal tumours from northern India

机译:印度北部皮肤阑尾肿瘤的临床病理研究

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Background: The skin appendageal tumours (ATs) encompass a wide variety of tumours clinically presenting as papules and nodules and with histologically distinct features. Early recognition of skin adnexal tumours is very important aspect as far as patient management and prognosis is concerned. The main of the study was to analyse and ascertain clinico-pathological study of skin appendageal tumours in a tertiary care centre. Methods: Retrospective cohort of patients with confirmed diagnosis of AT during 1st January 2013 to 31st December 2015 formed the study population. Study tools were records of the patients such as information from MRD (Medical Record Department) and records from histopathological section i.e. histopathological requisition forms and clinical case sheets. Cases clinically diagnosed as appendageal tumours, but not histologically, were excluded from the study. Results: Finally a total of 48 cases were included in this study. Mean age of onset was 22.7±6.4 years and the duration of complaints 5.34 ± 4.5 years. Benign follicular, benign eccrine, benign sebaceous and benign apocrine tumours were observed to be 48.89%, 42.22%, 2.22% and 6.67% respectively. Regarding distribution of benign and malignant tumours, among the all types of skin appendageal tumours diagnosed, 93.75% (N=45) were benign and 6.25% (N=3) were malignant. Pilomatricoma (54.54%), eccrine acrospiroma (26.31%) and syringocystadenoma papilliferum (67%) were observed as most commonly distributed histopathological types of diagnosed benign follicular, benign eccrine and benign apocrine tumours. Number of benign skin appendageal tumours was found maximum (n=25) in the age group of 26-50 years in both the sexes whereas malignant skin appendageal tumours were observed only (n=3) in the age group of 51-75 years in both the sexes. Conclusions: Findings of this study can be utilized to suspect type of AT thus helping in diagnosis. Profile, pattern and clinical appearance can serve as vital clue though histological confirmation is mandatory to confirm.
机译:背景:皮肤阑尾肿瘤(ATs)涵盖了临床上表现为丘疹和结节且具有组织学上不同特征的多种肿瘤。就患者管理和预后而言,皮肤附件肿瘤的早期识别是非常重要的方面。该研究的主要目的是在三级护理中心分析和确定皮肤阑尾肿瘤的临床病理研究。方法:回顾性队列研究对象为2013年1月1日至2015年12月31日确诊为AT的患者。研究工具是患者的记录,例如来自MRD(病历部门)的信息以及组织病理学部分的记录,即组织病理学申请表和临床病例表。该临床研究排除了临床诊断为阑尾肿瘤但在组织学上并非如此的病例。结果:最终总共48例被纳入本研究。平均发病年龄为22.7±6.4岁,投诉持续时间为5.34±4.5岁。良性滤泡性,良性内分泌性,皮脂性和良性顶分泌性肿瘤分别为48.89%,42.22%,2.22%和6.67%。关于良性和恶性肿瘤的分布,在诊断出的所有类型的皮肤阑尾肿瘤中,良性占93.75%(N = 45),恶性占6.25%(N = 3)。乳头状瘤(54.54%),内分泌性顶螺旋体瘤(26.31%)和乳突囊性腺瘤(67%)被认为是诊断为良性滤泡性,良性内分泌性和良性顶分泌肿瘤的最常见的组织病理学类型。在26-50岁的男女中,发现良性皮肤阑尾肿瘤的数量最多(n = 25),而在51-75岁的年龄组中仅观察到恶性的皮肤阑尾肿瘤(n = 3)。男女两性。结论:本研究的发现可用于怀疑AT的类型,从而有助于诊断。尽管必须通过组织学确认来确认,但轮廓,样式和临床外观仍可作为重要线索。

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