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首页> 外文期刊>International Journal of Reproduction, Contraception, Obstetrics and Gynecology >Role of sunshine vitamin ?D? sufficiency in male and female infertility
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Role of sunshine vitamin ?D? sufficiency in male and female infertility

机译:阳光中维生素D的作用男性和女性不育的充足性

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摘要

Infertility is a complex disorder which affects about 15% of couple. Animal and human studies suggest that vitamin D deficiency is involved in both male and female infertility. The expression levels of vitamin D receptors and CYP24A1 in human spermatozoa serve as positive predictive markers of semen quality. In women, vitamin D status has been associated with better IVF outcomes, anti Mullerian hormone production and maintenance of ovarian reserve. Serum [25(OH)] D levels have a direct relationship with clinical pregnancy outcomes in women undergoing IVF. Women with sufficient levels of vitamin D show higher implantation rates, higher rates of clinical pregnancy in IVF and ET cycles. In women undergoing IVF, higher vitamin levels in their serum and follicular fluid are more likely to achieve clinical pregnancy. Its most important role in reproduction may be at the endometrial level.
机译:不孕症是一种复杂的疾病,大约影响15%的夫妻。动物和人体研究表明,维生素D缺乏症与男性和女性不育都有关系。人体精子中维生素D受体和CYP24A1的表达水平是精液质量的阳性预测指标。在女性中,维生素D的状态与IVF结局,抗苗勒氏激素产生和维持卵巢储备有关。接受IVF的妇女的血清[25(OH)] D水平与临床妊娠结局有直接关系。维生素D含量充足的妇女在IVF和ET周期中显示出较高的着床率,临床妊娠率。在接受试管婴儿的妇女中,较高的血清和卵泡液中的维生素水平更有可能实现临床妊娠。它在生殖中最重要的作用可能在于子宫内膜。

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