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首页> 外文期刊>Iranian journal of psychiatry. >Escitalopram in Preschool-Age Children Diagnosed with ?Obsessive ?Compulsive? ?Disorder: A Case Report?
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Escitalopram in Preschool-Age Children Diagnosed with ?Obsessive ?Compulsive? ?Disorder: A Case Report?

机译：依西酞普兰诊断为“强迫症”，“强迫症”的学龄前儿童疾病：病例报告

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When a literature review on pediatric obsessive-compulsive disorder (OCD) is ?performed, it is observed that there is a dearth of research on preschool period OCD ?cases. Although cognitive behavioral therapy is recommended as the first line of ?treatment in preschool OCD cases when patients do not show adequate response to ?CBT, psychopharmacological treatment offers an alternative. The first line used in ?psychopharmacological treatment is selective serotonin reuptake inhibitors (SSRI’s). ?However, no SSRI’s (or any other drug group) have been approved by the FDA for this ?age group. Moreover, studies related to psychopharmacology in preschool OCD are very ?limited in the literature, consisting mostly of case reports related to sertraline and ?fluoxetine. In those studies, it is reported that sertraline and fluoxetine are effective in ?preschool OCD and generally well-tolerated. In this paper, we discussed the treatment ?and six-month follow-up period of a 3.5 year-old (42 months) female diagnosed with ?OCD and for whom escitalopram was used. In the literature, there is a retrospective case ?series related to this subject consisting of eleven cases, where improvement in symptoms ?is reported with escitalopram treatment in the five of six cases diagnosed with OCD. As ?far as we could find in literature, our paper is the second report on this subject. Our case ?also included the youngest patient to receive escitalopram for preschool period OCD ?and report its benefits.?
机译：当对儿童强迫症（OCD）进行文献综述时，发现对学龄前强迫症病例的研究还很匮乏。尽管在学龄前强迫症患者中，当对患者未对CBT表现出足够的反应时，建议将认知行为疗法作为第一疗法，但心理药物治疗是另一种选择。心理药物治疗中使用的第一行是选择性5-羟色胺再摄取抑制剂（SSRI）。但是，美国食品药品监督管理局（FDA）尚未批准该年龄组使用SSRI（或任何其他药物组）。此外，有关学龄前强迫症中心理药理学的研究在文献中非常有限，主要包括与舍曲林和氟西汀有关的病例报告。在那些研究中，据报道舍曲林和氟西汀在学龄前强迫症中有效，并且通常被良好耐受。在本文中，我们讨论了3.5岁（42个月）诊断为OCD并使用依他普仑的女性的治疗和六个月的随访期。在文献中，有一个回顾性病例系列涉及此主题，由11例组成，其中依他普仑治疗的6例确诊为OCD的患者中有5例症状有所改善。据我们在文献中所发现的，我们的论文是关于该主题的第二份报告。我们的病例还包括最年轻的接受依他普仑治疗学前期强迫症的患者，并报告其获益。

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