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首页> 外文期刊>Italian Journal of Medicine >Patent foramen ovale and ischemic stroke: more shadows than lights? What the internist should know
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Patent foramen ovale and ischemic stroke: more shadows than lights? What the internist should know

机译：卵圆孔未闭和缺血性中风：阴影多于光？内科医生应该知道什么

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摘要

The foramen ovale (FO) is an anatomical structure normally present in the fetus, which can persist in up to 25%-30% of the general population after birth. Normally it does not cause any harm but it has been associated with different pathological conditions; the more frequently encountered in clinical practice is an ischemic stroke or transient ischemic attack without any recognizable cause. However, a causal link between the cerebrovascular event and a right to left shunt through the FO is hard to demonstrate in most cases and which is the best treatment for secondary prevention is still a matter of debate with antithrombotic therapy or transcatheter closure of the FO as possible options. No definitive evidence of which is the most effective treatment is actually available so that a careful evaluation of each single patient is mandatory in order to select who will probably benefit the most from the interventional treatment as opposed to who will reasonably do well with medical therapy alone.
机译：卵圆孔（FO）是通常存在于胎儿中的解剖结构，出生后可以持续存在于普通人群的25％-30％。通常它不会造成任何伤害，但它与不同的病理状况有关;在临床实践中，最常见的是缺血性中风或短暂性脑缺血发作而没有任何可识别的原因。然而，在大多数情况下，很难证明脑血管事件与通过FO从右向左分流之间的因果关系，对于二级预防的最佳治疗仍是抗血栓治疗或经导管封堵FO的争议，因为可能的选择。实际上，没有确切的证据是最有效的治疗方法，因此必须对每位患者进行仔细评估，以选择谁将从干预治疗中受益最大，而不是合理地单独接受药物治疗。

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