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首页> 外文期刊>Eastern Journal of Medicine >Evaluation of Subclinical Papilledema in Patients with Obstructive Sleep Apnea Syndrome
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Evaluation of Subclinical Papilledema in Patients with Obstructive Sleep Apnea Syndrome

机译：梗阻性睡眠呼吸暂停综合症患者亚临床无水肿的评估

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Evaluation of Subclinical Papilledema in Patients with Obstructive Sleep Apnea Syndrome Zeynep Gürsel ?zkurt sup1/sup, Melike Demirsup2/sup, Yusuf Y?ld?r?msup3/sup, Selahattin Balsaksup3/sup, ümit Karaalpsup4/sup sup1/supDicle University Medical Faculity Ophthalmology Department, Diyarbakir, Turkey sup2/supDicle University Medical Faculity Thorax Diseases Department, Diyarbakir, Turkey sup3/supGazi Yasargil Education and Research Hospital Ophthalmology Department, Diyarbakir, Turkey sup4/supBatman Area Hospital Ophthalmology Department, Batman, Turkey INTRODUCTION: The aim of this study is to analyze optic nerve head total retinal thickness (TRT) in Obstructive Sleep Apnea Syndrome (OSAS) and demonstrate a possible subclinical papilledema METHODS: Thirty-six patients with suspected OSAS underwent standard overnight polysomnography and were grouped into mild, moderate and severe. Seventy eyes of thirty six OSAS patients and seventy-two eyes of healthy controls were included. Retinal nerve fiber layer thicknesses (RNLF) and TRT s were measured by optic coherence tomography. RESULTS: RNFL segment values showed no difference between OSAS and control groups. RNFL superior segment and inferonasal segments of the mild OSAS subgroup were found to be thinner than the moderate and severe OSAS subgroups (p=0.034, p=0.025, respectively). RNFL point values also showed no difference between the two groups. The RNFL inferior point of the mild OSAS subgroup was found to be thinner than the moderate and severe subgroups (p=0.036). OSAS TRTs were thinner than the controls at inferior and temporal points (p=0.005, p=0.033, respectively). The TRT inferior point of the mild OSAS subgroup was found to be thinner than the moderate and severe subgroups (p=0.006). At all points RNFL values were subtracted from the TRT values and compared. At the temporal point the OSAS group?s TRT-RNFL was thinner than that of the control groups (p=0.029). DISCUSSION AND CONCLUSION: TRT measurements could not demonstrate a possible subclinical papilledema. Thinning of RNFL thickness and TRT in OSAS patients could be the result of hypoxemia related chronic atrophy.
机译：阻塞性睡眠呼吸暂停综合症患者的亚临床上睑下垂的评估ZeynepGürsel？zkurt 1 ，Melike Demir 2 ，Yusuf Y？ld？r？m 3 ，Selahattin Balsak 3 ，ümitKaraalp 4 1 Dicle大学迪卡巴克尔大学眼科眼科 2 Dicle土耳其迪亚巴克尔大学医学中心胸腔疾病科 3 土耳其迪亚巴克尔加济Yasargil教育研究医院眼科 4 土耳其巴特曼巴特曼地区医院眼科简介：这项研究的目的是分析阻塞性睡眠呼吸暂停综合症（OSAS）的视神经乳头总视网膜厚度（TRT），并证明可能的亚临床性视乳头水肿。方法：对36例怀疑OSAS的患者进行了标准的夜间多导睡眠监测，并将其分为轻度，中度和严重。包括三十六名OSAS患者的七十只眼和健康对照的七十二只眼。视网膜神经纤维层厚度（RNLF）和TRTs通过光学相干断层扫描测量。结果：RNFL段值显示OSAS和对照组之间没有差异。发现轻度OSAS亚组的RNFL上段和鼻下肌段比中度和重度OSAS亚组薄（分别为p = 0.034，p = 0.025）。 RNFL点值在两组之间也没有差异。发现轻度OSAS亚组的RNFL下点比中度亚组和重度亚组薄（p = 0.036）。 OSAS TRT在下和颞点均较对照薄（分别为p = 0.005，p = 0.033）。发现轻度OSAS亚组的TRT下点比中度亚组和重度亚组薄（p = 0.006）。在所有点上，从TRT值中减去RNFL值并进行比较。在时间点上，OSAS组的TRT-RNFL比对照组薄（p = 0.029）。讨论与结论：TRT测量不能证明可能存在亚临床性乳头水肿。 OSAS患者的RNFL厚度和TRT变薄可能是与低氧血症相关的慢性萎缩的结果。

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