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Psychosis with vitamin B12 deficiency and increased extrapyramidal side effects: A case report

机译：维生素B12缺乏症和锥体束外副作用增加的精神病：一例报告

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Psychosis with vitamin B12 deficiency and increased extrapyramidal side effects: A case report Emine Füsun Akyüz ?im 1 , ?zgür Deniz De?er 1 Vitamin B12 is a methyl donor important for the continuity of neuronal metabolism. Deficiency in vitamin B12 has been associated with a variety of neuropsychiatric pathologies that include extrapyramidal symptoms such as mood disorders, depressive disorder, delirium, and paranoid psychosis. Extrapyramidal symptoms are also associated with factors such as gender, age, and the presence of a mood disorder. Novel generation antipsychotics are less likely to cause extrapyramidal symptoms than typical antipsychotics due to their selective anti-dopaminergic action and antagonistic effects on serotonin receptors. The present case report describes a patient with psychosis in which a vitamin B12 deficiency not only complicated the treatment of extrapyramidal symptoms, but also tended to increase them.
机译：维生素B12缺乏症和锥体束外副作用增加的精神病：病例报告EmineFüsunAkyüz？im 1 ，？zgürDeniz De？er 1 维生素B12是对神经元新陈代谢的连续性。维生素B12缺乏与多种神经精神疾病有关，包括锥体束外症状，如情绪障碍，抑郁症，del妄和偏执性精神病。锥体外系症状还与诸如性别，年龄和情绪障碍的存在相关。新一代抗精神病药由于具有选择性的抗多巴胺能作用和对5-羟色胺受体的拮抗作用，因此与典型的抗精神病药相比，不太可能引起锥体束外症状。本病例报告描述了一种精神病患者，其中维生素B12缺乏症不仅使锥体束外症状的治疗复杂化，而且还会加剧这些症状。

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