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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Hepatocellular carcinoma in Yemeni patients: a single centre experience over an 8-year period
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Hepatocellular carcinoma in Yemeni patients: a single centre experience over an 8-year period

机译:也门患者的肝细胞癌:为期8年的单中心经验

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We carried out a retrospective study of all patients admitted to Al-Thawra Teaching Hospital in Sana’a with hepatocellular carcinoma to study the disease profile in Yemeni patients and identify possible risk factors. During the 8-year study period, January 2001–December 2008, 251 patients were admitted with confirmed hepatocellular carcinoma. From hospital records we collected data on demographic characteristics, clinical manifestations, histological characters, viral markers, treatment and outcome. Around 75% of the patients were males. Age range was 26–75 years, mean 53.5 (SD 13.9) years. Most patients were farmers (73.7%) and had a history of chemical contact. Chronic hepatitis B virus infection (48.2 %) and hepatitis C virus infection (38.2%) were the most frequently identified risk factors. Qat chewing and smoking were not statistically significant risk factors. Right lobe involvement was seen in 109 (43.4%) patients and 154 (61.4%) presented with multiple lesions. We found 187 (74.0%) patients had cirrhotic liver associated with hepatocellular carcinoma. Overall mortality rate within 6 months of admission to hospital was 24.3%.
机译:我们对在萨那的Al-Thawra教学医院住院的所有患有肝细胞癌的患者进行了回顾性研究,以研究也门患者的疾病状况并确定可能的危险因素。在为期8年的研究期间(2001年1月至2008年12月),有251例确诊为肝细胞癌的患者入院。从医院记录中,我们收集了有关人口统计学特征,临床表现,组织学特征,病毒标志物,治疗和预后的数据。大约75%的患者是男性。年龄范围是26-75岁,平均53.5(SD 13.9)岁。大多数患者是农民(73.7%),并且有化学接触史。慢性乙型肝炎病毒感染(占48.2%)和丙型肝炎病毒感染(占38.2%)是最常见的危险因素。 Qat咀嚼和吸烟不是统计学上显着的危险因素。 109例(43.4%)患者中有右叶受累,154例(61.4%)患者有多处病变。我们发现187例(74.0%)肝硬化合并肝细胞癌。入院6个月内的总死亡率为24.3%。

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