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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >High incidence of hepatitis B infection after treatment for paediatric cancer at a teaching hospital in Baghdad
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High incidence of hepatitis B infection after treatment for paediatric cancer at a teaching hospital in Baghdad

机译:巴格达一家教学医院治疗小儿癌症后乙型肝炎感染率高

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This study estimated the incidence of viral hepatitis in children treated for cancer, to identify variables that could affect this incidence and to assess the role of hepatitis B virus (HBV) vaccination in preventing infection. Between September 2007 and June 2008, 256 children in the haemato-oncology unit at the Children’s Welfare Teaching Hospital, Baghdad, were studied prospectively. Demographic and clinical data and vaccination history were recorded. Patients were tested for HBV at the time of diagnosis (all were negative) and after starting chemotherapy. On admission to the unit, 231 patients (90.2%) were revaccinated. At reassessment after treatment for cancer, HBV infection was found in 70 patients (27.3%). The variables that significantly increased the risk for HBV infection were a diagnosis of leukaemia and receiving more than 3 units of blood. A higher number of HBV vaccinations in hospital reduced the risk for HBV infection. The high rate of acquisition of HBV infection found in this study indicates the need for better screening of blood products and adherence to aseptic techniques in management of this group of patients.
机译:这项研究估计了接受癌症治疗的儿童中病毒性肝炎的发病率,以识别可能影响该发病率的变量,并评估乙肝病毒(HBV)疫苗接种在预防感染中的作用。在2007年9月至2008年6月之间,对巴格达儿童福利教学医院血液肿瘤科的256名儿童进行了前瞻性研究。记录人口统计和临床数据以及疫苗接种史。在诊断时(均阴性)和开始化疗后对患者进行了HBV检测。入院时,有231名患者(90.2%)进行了重新接种。在对癌症治疗后进行重新评估时,发现70例患者(27.3%)的HBV感染。显着增加HBV感染风险的变量是白血病的诊断和接受超过3个单位的血液。医院中更多的HBV疫苗接种减少了HBV感染的风险。在这项研究中发现的高获得性HBV感染率表明,在这类患者的治疗中需要更好地筛查血液制品和遵守无菌技术。

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