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Common errors in the treatment of intra-abdominal infections: the irrational use of antimicrobial agents

机译:腹腔内感染的常见错误:不合理使用抗菌药物

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Antimicrobial resistance is a global, emergent problem because an increasing numbers of serious community acquired and nosocomial infections are caused by resistant bacterial pathogens. It is a direct consequence of the excessive and irrational use of antibiotics. The use of antimicrobial agents is very high, often improper, in the department of general and emergency surgery and in the Intensive Cure Units to decrease morbidity and mortality rate related to intra-abdominal infections. Source control and empiric antibiotic therapy have to be administrated as early as possible to decrease high mortality rates in patients with severe sepsis or septic shock and, in this, the general surgeon has a crucial role. Proper antimicrobial stewardship in selecting an appropriate antibiotic and optimizing its dose and duration to cure intra-abdominal infections may prevent the emergence of AR and decrease costs for antibiotics.
机译:抗菌素耐药性是一个全球性的紧急问题,因为越来越多的严重社区获得性感染和医院感染是由耐药菌病原体引起的。这是过度和不合理使用抗生素的直接后果。在普通外科和急诊外科以及在重症监护室使用抗菌药物的比例很高,通常不当,以降低与腹腔内感染有关的发病率和死亡率。必须尽早进行源控制和经验性抗生素治疗,以降低严重脓毒症或败血性休克患者的高死亡率,在这种情况下,普通外科医师起着至关重要的作用。在选择合适的抗生素并优化其剂量和持续时间以治愈腹腔内感染方面进行适当的抗菌管理可以防止AR的出现并降低抗生素的成本。

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