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Estimating the prevalence of dementia using multiple linked administrative health records and capture–recapture methodology

机译：使用多个链接的行政健康记录和捕获-再捕获方法估算痴呆的患病率

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BackgroundObtaining population-level estimates of the incidence and prevalence of dementia is challenging due to under-diagnosis and under-reporting. We investigated the feasibility of using multiple linked datasets and capture–recapture techniques to estimate rates of dementia among women in Australia. MethodsThis work is based on the Australian Longitudinal Study on Women’s Health. A random sample of 12,432 women born in 1921–1926 was recruited in 1996. Over 16?years of follow-up records of dementia were obtained from five sources: three-yearly self-reported surveys; clinical assessments for aged care assistance; death certificates; pharmaceutical prescriptions filled; and, in three Australian States only, hospital in-patient records. ResultsA total of 2534 women had a record of dementia in at least one of the data sources. The aged care assessments included dementia records for 79.3% of these women, while pharmaceutical data included 34.6%, death certificates 31.0% and survey data 18.5%. In the States where hospital data were available this source included dementia records for 55.8% of the women. Using capture–recapture methods we estimated an additional 728 women with dementia had not been identified, increasing the 16?year prevalence for the cohort from 20.4 to 26.0% (95% confidence interval [CI] 25.2, 26.8%). ConclusionsThis study demonstrates that using routinely collected health data with record linkage and capture–recapture can produce plausible estimates for dementia prevalence and incidence at a population level.
机译：背景技术由于诊断不足和报告不足，因此难以获得对痴呆症发病率和患病率的总体水平的估计。我们调查了使用多个链接的数据集和捕获-再捕获技术来估计澳大利亚女性痴呆率的可行性。方法：这项工作基于澳大利亚妇女健康纵向研究。 1996年随机抽取了19432年至1921年至1926年出生的12,432名妇女的样本。对痴呆症的16年跟踪记录来自以下五个方面：三年一次自我报告的调查;老年护理援助的临床评估;死亡证明;填写药品处方;仅在澳大利亚的三个州提供住院住院记录。结果至少有一个数据来源中，共有2534名妇女患有痴呆症记录。老年护理评估包括这些妇女中79.3％的痴呆记录，而药物数据包括34.6％，死亡证明书31.0％和调查数据18.5％。在可获得医院数据的国家中，该来源包括痴呆症记录，占55.8％的女性。使用捕获-捕获方法，我们估计还没有发现728名痴呆妇女，使该人群的16年患病率从20.4％增加到26.0％（95％置信区间[CI] 25.2，26.8％）。结论：这项研究表明，将常规收集的健康数据与记录联系和捕获-再捕获结合使用，可以对人群中痴呆的患病率和发病率做出合理的估计。

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