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首页> 外文期刊>Endoscopy International Open >Transpapillary biliary stenting is a risk factor for pancreatic stones in patients with autoimmune pancreatitis
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Transpapillary biliary stenting is a risk factor for pancreatic stones in patients with autoimmune pancreatitis

机译:乳头状胆道支架置入术是自身免疫性胰腺炎患者胰腺结石的危险因素

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Background and study aim: Pancreatic stones occasionally develop in autoimmune pancreatitis (AIP), often worsen endocrine and exocrine functions, and occasionally cause pain attacks. However, the risks of pancreatic stones in AIP have been poorly studied. The aim of this study was to analyze the risk factors associated with pancreatic stone formation in cases of AIP. Patients and methods: In total, 50 patients with AIP (39 males, 11 females; mean age 64.0 years), followed up for at least a year, were analyzed for their demographic and clinical findings and pancreatic stone occurrence. Results: In total, 50 patients were followed up for an average of 59.7 (12?–?120) months, with steroid treatment in 44 patients (88?%); pancreatic stones occurred in 14 (28?%) patients after the diagnosis of AIP and endoscopic treatment was needed in one patient with pain attack. The pancreatic stones appeared only in patients with long follow-up period (P?
机译:背景和研究目的:胰腺结石偶尔会在自身免疫性胰腺炎(AIP)中发展,常常使内分泌和外分泌功能恶化,并偶尔引起疼痛发作。但是,对AIP中胰腺结石的风险研究很少。这项研究的目的是分析AIP病例中与胰腺结石形成相关的危险因素。患者和方法:总共分析了50例AIP患者(男39例,女11例;平均年龄64.0岁),随访了至少一年,分析了他们的人口统计学和临床​​表现以及胰腺结石的发生情况。结果:总共50例患者接受了平均59.7(12?–120)个月的随访,接受类固醇治疗的患者为44例(88%)。诊断为AIP后,有14位(28%)的患者发生了胰腺结石,一名疼痛发作的患者需要进行内镜治疗。胰腺结石仅出现在随访时间较长(P <0.001,83.9个月vs.49.6个月),胆道支架置入(优势比[OR]:8.40,P?=?0.010),复发(OR: 6.20,P = 0.023,黄疸(OR:5.40,P = 0.019)和十二指肠大乳头肿胀(OR:4.67,P = 0.040)。在27例患者中,胆道支架置入术平均需要9.9个月。多变量分析显示仅与胆道支架置入有显着相关性(P = 0.011)。在主胰管或圣托里尼管有结石的患者(22.1个月)出现结石的时间要比在其他地方发生胰结石的患者(53.4个月)的出现时间早(P≤0.018)。结论:在AIP患者中放置胆道支架时应考虑胰腺结石发展的风险。

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