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Lifestyle domains as determinants of wheeze prevalence in urban and rural schoolchildren in Ecuador: cross sectional analysis

机译:生活方式领域是厄瓜多尔城乡学童喘息流行的决定因素:横断面分析

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Background The acquisition of a modern lifestyle may explain variations in asthma prevalence between urban and rural areas in developing countries. However, the effects of lifestyle on asthma have been investigated as individual factors with little consideration given to the effects of lifestyle as a set of attributes. The aim of the present study was to identify modern lifestyle domains and assess how these domains might explain wheeze prevalence in urban and rural areas. Methods We analysed data from cross-sectional studies of urban and rural schoolchildren in Esmeraldas Province, Ecuador. Variables were grouped as indicators of socioeconomic factors, sedentarism, agricultural activities and household characteristics to represent the main lifestyle features of the study population. We used multiple correspondence analyses to identify common lifestyle domains and cluster analysis to allocate children to each domain. We evaluated associations between domains and recent wheeze by logistic regression. Results We identified 2–3 lifestyle domains for each variable group. Although wheeze prevalence was similar in urban (9.4%) and rural (10.3%) schoolchildren, lifestyle domains presented clear associations with wheeze prevalence. Domains relating to home infrastructure (termed transitional, rudimentary, and basic urban) had the strongest overall effect on wheeze prevalence in both urban (rudimentary vs. basic urban, OR?=?2.38, 95% CI 1.12-5.05, p?=?0.024) and rural areas (transitional vs. basic urban, OR?=?2.02, 95% CI 1.1-3.73, p?=?0.024; rudimentary vs. basic urban, OR?=?1.88, 95% CI 1.02-3.47, p?=?0.043). A high level of sedentarism was associated with wheeze in the rural areas only (OR?=?1.64, 95% CI 1.23-2.18, p?=?0.001). Conclusions We identified lifestyle domains associated with wheeze prevalence, particularly living in substandard housing and a high level of sedentarism. Such factors could be modified through programmes of improved housing and education. The use of lifestyle domains provides an alternative methodology for the evaluation of variations in wheeze prevalence in populations with different levels of development.
机译:背景技术现代生活方式的获得可以解释发展中国家城乡之间哮喘患病率的差异。然而,已经将生活方式对哮喘的影响作为个体因素进行了研究,很少考虑将生活方式作为一组属性的影响。本研究的目的是确定现代生活方式领域,并评估这些领域如何解释城市和农村地区的喘息流行。方法我们分析了厄瓜多尔埃斯梅拉达斯省城市和农村学龄儿童的横断面研究数据。变量被分组为社会经济因素,久坐,农业活动和家庭特征的指标,以代表研究人群的主要生活方式。我们使用了多种对应关系分析来识别常见的生活方式领域,并进行聚类分析以将孩子分配到每个领域。我们通过逻辑回归评估了领域与近期喘息之间的关联。结果我们为每个变量组确定了2–3个生活方式领域。尽管城市(9.4%)和农村(10.3%)学童的喘息流行率相似,但生活方式域与喘息流行率之间存在明显关联。与家庭基础设施相关的领域(称为过渡性,基本性和基本性城市)在两个城市(基本性相对于基本性城市,OR = 2.38,95%CI 1.12-5.05,p?=?)中对喘息流行的总体影响最大。 0.024)和农村地区(过渡性城市人口与基本城市人口的比较,OR?=?2.02,95%CI 1.1-3.73,p?=?0.024;基本城市人口与基本城市,OR?=?1.88,95%CI 1.02-3.47, p≥0.043)。久坐感的高发仅与农村地区的喘息有关(OR≥1.64,95%CI 1.23-2.18,P≥0.001)。结论我们确定了与喘息流行相关的生活方式领域,尤其是居住在不合标准的住房和高度的久坐感中。这些因素可以通过改善住房和教育的方案加以修改。生活方式域的使用为评估具有不同发展水平的人群的喘息流行率变化提供了另一种方法。

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