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首页> 外文期刊>European Journal of Medicinal Plants >Antibacterial and Antifungal Activity of Litsea monopetala Leaves on Selected Pathogenic Strains
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Antibacterial and Antifungal Activity of Litsea monopetala Leaves on Selected Pathogenic Strains

机译：紫荆叶对某些病原菌的抗菌和抗真菌活性

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Aims: To evaluate the antibacterial and antifungal activity of some solvent extracts of Litsea monopetala (LM) leaves. Study Design: Examination of antibacterial and antifungal activity of petroleum ether fraction (PEF), chloroform fraction (CLF), ethyl acetate fraction (EAF) and crude methanol extract (CME) of Litsea monopetala (LM) leaves. Place and Duration of Study: Department of Pharmacy, Southeast University, Dhaka-1213, Bangladesh, from September to November 2014. Methodology: Fresh LM leaves were extracted with methanol followed by fractionation. Antibacterial and antifungal activities of the crude extract were determined by using the Agar disk diffusion method against gram positive, gram negative bacterial and fungal strains. Results: All tested plant extracts, showed varying zones of inhibition against bacteria and fungi tested. The zone of inhibition for bacteria was found to be in the range from 5 to 15 mm and 5 to 13 mm for fungi. The CME and EAF of the methanolic extract of LM has greater antibacterial activity against all tested gram positive and gram negative bacteria compare to other fraction. CME and EAF has also strong antifungal activity against tested fungi except Candida albicans in which CLF showed maximum antifungal activity. Conclusion: The present study shows that LM leaves possess an excellent source of natural antibacterial and antifungal agents which could be developed in the treatment of bacterial and fungal diseases.
机译：目的：评估Litsea monopetala（LM）叶片的某些溶剂提取物的抗菌和抗真菌活性。研究设计：检测Litsea monopetala（LM）树叶的石油醚馏分（PEF），氯仿馏分（CLF），乙酸乙酯馏分（EAF）和粗甲醇提取物（CME）的抗菌和抗真菌活性。研究的地点和时间：2014年9月至2014年11月，东南大学药学院，孟加拉国达卡1213。方法：用甲醇提取新鲜的LM叶片，然后分级分离。通过使用琼脂圆盘扩散法测定粗提取物对革兰氏阳性，革兰氏阴性细菌和真菌菌株的抗菌和抗真菌活性。结果：所有测试的植物提取物均显示出不同的对细菌和真菌的抑制作用区域。发现对细菌的抑制区域在5mm至15mm的范围内，对于真菌而言，在5mm至13mm的范围内。与其他级分相比，LM甲醇提取物的CME和EAF对所有测试的革兰氏阳性和革兰氏阴性细菌具有更大的抗菌活性。 CME和EAF对测试的真菌也具有很强的抗真菌活性，除了白色念珠菌（其中CLF表现出最大的抗真菌活性）。结论：本研究表明，LM叶具有天然抗菌和抗真菌剂的优良来源，可用于治疗细菌和真菌疾病。

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