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首页> 外文期刊>European Journal of Medicinal Plants >In vitro Antioxidant, Antimicrobial, Insecticidal and Cytotoxic Activities of the Medicinal Plants: Allamanda cathartica and Mimusops elengi
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In vitro Antioxidant, Antimicrobial, Insecticidal and Cytotoxic Activities of the Medicinal Plants: Allamanda cathartica and Mimusops elengi

机译：药用植物的体外抗氧化剂，抗微生物剂，杀虫剂和细胞毒性活性：阿拉曼兰（Allamanda cathartica）和Mi（Mimusops elengi）

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A comparison of in vitro antioxidant, antimicrobial, insecticidal and cytotoxic activities of two medicinal plants, Allamanda cathartica and Mimusops elengi have been studied by spectrophotometric and disk diffusion methods in this research. It was observed that different leaf extract of A. cathartica exhibited less antioxidant activity in comparison to that of the extract of M. elengi. The highest antioxidant activity (4.588±0.001 mg/mL) was found in the dia-ion resin adsorbed fraction of M. elengi and the least activity (1.82±0.002 mg/mL) was found in the methanolic fraction of A. cathartica . From the results of antimicrobial activity test, it was observed that the petroleum ether fraction of A. cathartica showed the maximum inhibition with the diameter of 16–20 mm while the ethyl acetate fraction of M. elengi showed the least inhibition with the diameter of 10–16 mm. The insecticidal activity against the pathogenic bacteria Tribolium castaneum of A. cathartica was very pronounced with the LD50 values of 225.205 μg/cm2 where as M. elengi showed the least and/or no insecticidal activity. All the extracts such as methanol, petroleum ether, chloroform, ethyl acetate and dia-ion-resin adsorbed fraction of both A. cathartica and M. elengi displayed higher level of toxicity towards brine shrimps lethality bioassay. Based on the results obtained, the A. cathartica and M. elengi leaf extracts could serve as the potential source of natural antioxidant, antimicrobial and anticancer agents. Also they could be used for the treatments of different oxidative disorders, infection diseases caused by the resistant microorganisms and cancer cells, respectively.
机译：本研究通过分光光度法和圆盘扩散法研究了两种药用植物阿拉曼达（Allamanda cathartica）和Mi鼠（Mimusops elengi）的体外抗氧化，抗菌，杀虫和细胞毒性活性的比较。观察到，与艾美分支杆菌提取物相比，不同的叶楠提取物叶具有较低的抗氧化活性。钙离子吸附的艾氏支原体的馏分中发现最高的抗氧化活性（4.588±0.001 mg / mL），而薄荷草的甲醇馏分中发现的最小抗氧化剂活性（1.82±0.002 mg / mL）。从抗菌活性测试结果可以看出，直径为16–20 mm时，A。cathartica的石油醚部分显示出最大的抑制作用，而直径为10时，M。elengi的乙酸乙酯部分显示出最小的抑制作用。 –16毫米。 LD.sub <50> 50 值为225.205μg/ cm 2 ，对夜蛾致病菌Tribolium castaneum的杀虫活性非常显着，其中M. elengi最少， /或没有杀虫活性。提取的所有提取物，例如甲醇，石油醚，氯仿，乙酸乙酯和重离子树脂吸附的部分提取物，都对盐水虾致死性生物测定具有较高的毒性。根据获得的结果，A。cathartica和M. elengi叶提取物可作为天然抗氧化剂，抗微生物剂和抗癌剂的潜在来源。它们也可以分别用于治疗由抗性微生物和癌细胞引起的各种氧化性疾病，感染性疾病。

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