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首页> 外文期刊>Eurosurveillance >Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013
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Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013

机译：使用基于发病率的残疾调整生命年（DALY）的传染病对人口健康的影响：欧洲和欧洲经济区国家（2009年至2013年）欧洲传染病负担研究的结果

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Background and aims The Burden of Communicable Diseases in Europe (BCoDE) study aimed to calculate disability-adjusted life years (DALYs) for 31 selected diseases in the European Union (EU) and European Economic Area (EEA). Methods: DALYs were estimated using an incidence-based and pathogen-based approach. Incidence was estimated through assessment of data availability and quality, and a correction was applied for under-estimation. Calculation of DALYs was performed with the BCoDE software toolkit without applying time discounting and age-weighting. Results: We estimated that one in 14 inhabitants experienced an infectious disease episode for a total burden of 1.38 million DALYs (95% uncertainty interval (UI): 1.25–1.5) between 2009 and 2013; 76% of which was related to the acute phase of the infection and its short-term complications. Influenza had the highest burden (30% of the total burden), followed by tuberculosis, human immunodeficiency virus (HIV) infection/AIDS and invasive pneumococcal disease (IPD). Men had the highest burden measured in DALYs (60% of the total), adults?65 years of age and over had 24% and children?less than?5 years of age had 11%. Age group-specific burden showed that infants (less than?1 year of age) and elderly people (80 years of age and over) experienced the highest burden. Conclusions: These results provide baseline estimates for evaluating infectious disease prevention and control strategies. The study promotes an evidence-based approach to describing population health and assessing surveillance data availability and quality, and provides information for the planning and prioritisation of limited resources in infectious disease prevention and control.
机译：背景和目标欧洲传染病负担（BCoDE）研究旨在计算欧盟（EU）和欧洲经济区（EEA）中31种选定疾病的残疾调整生命年（DALYs）。方法：采用基于发病率和基于病原体的方法估算DALY。通过评估数据的可用性和质量来估计发病率，并对低估进行校正。 DALY的计算是使用BCoDE软件工具包进行的，而没有应用时间折扣和年龄加权。结果：我们估计，2009年至2013年间，每14个居民中就有1人经历了传染病发作，总负担为138万DALY（95％不确定区间（UI）：1.25–1.5）。其中76％与感染的急性期及其短期并发症有关。流感的负担最大（占总负担的30％），其次是肺结核，人类免疫缺陷病毒（HIV）感染/艾滋病和侵袭性肺炎球菌疾病（IPD）。男性的DALYs负担最大（占总数的60％），年龄在65岁及以上的成年人占24％，而年龄在5岁以下的儿童则占11％。特定年龄组的负担表明，婴儿（小于1岁）和老年人（80岁及以上）承受的负担最大。结论：这些结果为评估传染病的预防和控制策略提供了基线估计。该研究促进了一种基于证据的方法来描述人群健康并评估监视数据的可用性和质量，并为规划和确定传染病预防和控制中的有限资源的优先次序提供了信息。

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