首页> 外文期刊>Genomics >Genetic equidistance at nucleotide level
【24h】

Genetic equidistance at nucleotide level

机译:核苷酸水平的遗传等距

获取原文
           

摘要

The genetic equidistance phenomenon shows complex taxa to be all approximately equidistant to a less complex species in amino acid percentage identity. The overlooked mystery was re-interpreted by the maximum genetic diversity hypothesis (MGD). Here, we studied 14 proteomes and their coding DNA sequences (CDS) to see if the equidistance phenomenon also holds at the CDS level. We found that the outgroup taxon was equidistant to the two more complex taxa species. When two sister taxa were compared to human as the outgroup, the more complex taxon was closer to human, confirming species complexity to be the primary determinant of MGD. Finally, we found the fraction of overlap sites to be inversely correlated with CDS conservation, indicating saturation to be more common in less conserved DNAs. These results establish the genetic equidistance phenomenon to be universal at the DNA level and provide additional evidence for the MGD theory.
机译:遗传等距现象表明,复杂的分类单元在氨基酸百分比同一性上都几乎与较不复杂的物种等距。最大遗传多样性假设(MGD)重新解释了被忽视的谜团。在这里,我们研究了14个蛋白质组及其编码DNA序列(CDS),以查看等距现象是否也适用于CDS级别。我们发现外群分类单元与两个更复杂的分类单元物种等距。当将两个姐妹分类单元与人类作为一个整体进行比较时,较复杂的分类单元更接近人类,从而证实物种复杂性是MGD的主要决定因素。最后,我们发现重叠位点的分数与CDS保守性成反比,表明饱和度在保守性较低的DNA中更为常见。这些结果确定了遗传等距现象在DNA水平上是普遍的,并为MGD理论提供了额外的证据。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号