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Genetic equidistance at nucleotide level

机译:核苷酸水平的遗传等级

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The genetic equidistance phenomenon shows complex taxa to be all approximately equidistant to a less complex species in amino acid percentage identity. The overlooked mystery was re-interpreted by the maximum genetic diversity hypothesis (MGD). Here, we studied 14 proteomes and their coding DNA sequences (CDS) to see if the equidistance phenomenon also holds at the CDS level. We found that the outgroup taxon was equidistant to the two more complex taxa species. When two sister taxa were compared to human as the outgroup, the more complex taxon was closer to human, confirming species complexity to be the primary determinant of MGD. Finally, we found the fraction of overlap sites to be inversely correlated with CDS conservation, indicating saturation to be more common in less conserved DNAs. These results establish the genetic equidistance phenomenon to be universal at the DNA level and provide additional evidence for the MGD theory. (C) 2017 Elsevier Inc. All rights reserved.
机译:遗传等距离现象显示复杂的分类群,致近氨基酸百分比同一性近似等距。 被忽视的谜团被最大的遗传多样性假设(MGD)重新解释。 在这里,我们研究了14个蛋白质蛋白酶及其编码DNA序列(CDS),看看等距现象是否也在CDS级别持有。 我们发现除了另外两种复杂的分类群物种等等。 当两个姐妹的分类群被人类作为小组进行比较时,更复杂的分类群更接近人,确认物种复杂性是MGD的主要决定因素。 最后,我们发现与CDS守恒相关的重叠位点的分数,表明饱和度在不那么保守的DNA中更常见。 这些结果在DNA水平中建立了普遍的遗传等距现象,为MGD理论提供了额外的证据。 (c)2017年Elsevier Inc.保留所有权利。

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