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首页> 外文期刊>Geosciences >Exposure to Selected Geogenic Trace Elements (I, Li, and Sr) from Drinking Water in Denmark
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Exposure to Selected Geogenic Trace Elements (I, Li, and Sr) from Drinking Water in Denmark

机译：暴露于丹麦饮用水中选定的基因微量元素（I，Li和Sr）

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The naturally occurring geogenic elements iodine (I), lithium (Li), and strontium (Sr) have a beneficial effect on human health. Iodine has an essential role in human metabolism while Li and Sr are used, respectively, as a treatment for various mental disorders and for post-menopausal osteoporosis. The aim here is to evaluate the potential for future epidemiological investigations in Denmark of lifelong and chronic exposure to low doses of these compounds. The drinking water data represents approximately 45% of the annual Danish groundwater abstraction for drinking water purposes, which supplies approximately 2.5 million persons. The spatial patterns were studied using inverse distance weighted interpolation and cluster analysis. The exposed population was estimated based on two datasets: (1) population density in the smallest census unit, the parishes, and (2) geocoded addresses where at least one person is residing. We found significant spatial variation in the exposure for all three elements, related mainly to geochemical processes. This suggests a prospective opportunity for future epidemiological investigation of long-term effects of I, Li, and Sr, either alone or in combinations with other geogenic elements such as Ca, Mg or F.
机译：天然存在的地球成因元素碘（I），锂（Li）和锶（Sr）对人体健康具有有益作用。碘在人体新陈代谢中起着至关重要的作用，而Li和Sr分别用于治疗各种精神疾病和绝经后骨质疏松症。这里的目的是评估在丹麦进行的终身和长期暴露于低剂量这些化合物的流行病学调查的潜力。饮用水数据约占丹麦每年用于饮用水目的的地下水抽取量的45％，为大约250万人提供了饮用水。使用反距离加权插值和聚类分析研究了空间格局。根据两个数据集估算了暴露的人口：（1）人口普查最小的区域（教区）的人口密度，以及（2）至少有一个人居住的地理编码地址。我们发现所有这三个元素的暴露量都有明显的空间变化，主要与地球化学过程有关。这暗示了未来对I，Li和Sr的长期影响进行流行病学调查的潜在机会，无论是单独使用还是与其他地质元素（例如Ca，Mg或F）结合使用。

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