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Biomaterials in skull base surgery

机译:颅底手术中的生物材料

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Reconstruction materials and techniques for the base of the skull have undergone rapid developments and differentiation in recent years. While mostly autotransplants, collagens or resorbable alloplastic materials are preferred for duraplasties, pronounced organ-specific differences can be observed in the reconstruction of hard tissues. The use of polymethylmethacryl bone cement, once wide-spread, has decreased greatly due to the release of toxic monomers. Bony autotransplants are still used primarily for smaller skull-base defects, intraoperatively formable titanium nets may be also used for larger fronto- or laterobasal reconstructions of bony defects. Defects in visible areas are increasingly closed with preformed titanium or ceramic implants, which are planned and fitted to the individual patient using preoperative CT imaging. At the skull base, this applies especially to reconstructions of the frontal sinus. For extensive reconstructions of the orbita, titanium nets and non-resorbable plastics have proven valuable; in closing smaller defects especially of the orbital floor, resorbable implants based on Polyglactin 901 are also used.
机译:近年来,用于颅底的重建材料和技术经历了快速的发展和分化。尽管大多数自​​体移植,胶原蛋白或可吸收的异体材料是硬脑膜成形术的首选,但在硬组织的重建中可以观察到明显的器官特异性差异。聚甲基丙烯酸甲酯骨水泥一经广泛使用,由于有毒单体的释放而大大减少了使用。骨自体移植仍主要用于较小的颅骨缺损,术中可成形的钛网也可用于骨缺损的较大额叶或后基底重建。可见的区域中的缺陷越来越多地被预制的钛或陶瓷植入物封闭,这些植入物已通过术前CT成像计划并安装到各个患者身上。在颅底,这尤其适用于额窦的重建。对于大范围重建眼眶,钛网和不可吸收的塑料已被证明是有价值的。为了闭合较小的缺陷,尤其是眼眶底的较小缺陷,还使用了基于Polyglactin 901的可吸收植入物。

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