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首页> 外文期刊>Gynecologic Oncology Reports >Surgical management of cervical cancer by laparoscopy or laparotomy?
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Surgical management of cervical cancer by laparoscopy or laparotomy?

机译:腹腔镜或剖腹术对宫颈癌的外科治疗?

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In their closing remarks Leath III and Monk state that “Clinical trialwork from the GOG is changing the standard of care for all clinicalscenarios” (Leath & Monk, 2018). I strongly agree and for this reason Iwould like to open the discussion on surgery in cervical cancer basedupon the recently presented Laparoscopic Approach to Cervical Cancer(LACC) trial of the Global Gynecologic Oncology Consortium (G-GOC)(LACC/G-GOC-1001 trial; ClinicalTrials.gov Identifier: NCT00614211)(Ramirez et al., 2018; LACC Trials, n.d.) This randomized phase 3 trialtested the non-inferiority of minimal invasive radical hysterectomyversus abdominal radical hysterectomy in women with early-stagecervical cancer. The conclusions were that minimal invasive surgerywas associated with significant higher recurrence rates and a significantworse overall survival. Changing from minimal invasive surgery toopen surgery would reduce the number of recurrences by 6 and thenumber of deaths by 5 per 100. You can have a debate about the studyand do a SWOT analysis, but at the end of the day it is still level 1evidence (Tjalma, 2018).
机译:Leath III和Monk在闭幕词中表示:“ GOG的临床试验正在改变所有临床方案的护理标准”(Leath&Monk,2018年)。我非常同意,因此,我想基于最近在全球妇科肿瘤学联盟(G-GOC)(LACC / G-GOC-1001)提出的腹腔镜宫颈癌治疗(LACC)试验的基础上展开关于宫颈癌手术的讨论。试验; ClinicalTrials.gov标识符:NCT00614211)(Ramirez等人,2018; LACC试验,nd)该随机3期试验测试了早期宫颈癌女性患者微创根治性子宫切除术与腹部根治性子宫切除术之间的差异。结论是微创手术与较高的复发率和较差的总体生存率相关。从微创手术改为开放手术将使复发率降低6例,死亡人数减少100人中有5例。您可以对这项研究进行辩论并进行SWOT分析,但最终仍然是1级证据(恰尔马,2018年)。

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