...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Fisioterapia em Movimento >Associa??o entre mediadores inflamatórios, for?a de preens?o manual e mobilidade em idosos da comunidadeAsociación entre mediadores inflamatorios, fuerza de la empu?adura y la movilidad en ancianos de la comunidad
【24h】

Associa??o entre mediadores inflamatórios, for?a de preens?o manual e mobilidade em idosos da comunidadeAsociación entre mediadores inflamatorios, fuerza de la empu?adura y la movilidad en ancianos de la comunidad

机译：炎症介质，手动抓力和社区活动性之间的关联

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Introduction: Aging is associated with loss of muscle mass, immunosenescence and increased production of inflammatory mediators, high levels being predictors of a decline in functional capacity in the elderly. Objective: To assess the association between inflammatory mediators, interleukin 6 (IL-6) and C-reactive protein (CRP) and functional capacity in the elderly. Methods: Cross-sectional study with 308 community-dwelling elderly. The study was approved by the Research Ethics Committee, under protocol number 067/2010. Grip strength (GS) was measured using a JAMAR ? dynamometer and functional capacity by the Timed Up and Go (TUG) test. Blood tests were performed and serum levels of C-reactive protein and interleukin 6 assessed. Spearman’s coefficient was applied to analyze the correlation between variables and the Mann-Whitney for intergroup comparison. Significance was set at 0.05. Results: There was no significant correlation between GS, the TUG and inflammatory mediators (CRP and IL-6). However, by adjusting for variables such as age, sex and muscle mass, a significant and inverse correlation (p = 0.023) was observed between GS and CPR. Conclusion: Elderly subjects with low C-reactive protein levels performed better in the grip strength test. It is important to investigate the adverse effects on functional capacity that can be influenced by inflammatory cytokines in the elderly during aging.
机译：简介：衰老与肌肉量减少，免疫衰老和炎性介质的产生增加有关，高水平是老年人功能能力下降的预兆。目的：评估老年人的炎症介质，白介素6（IL-6）和C反应蛋白（CRP）与功能能力之间的关系。方法：对308名社区居民的老年人进行横断面研究。这项研究已由研究伦理委员会根据协议编号067/2010批准。握力（GS）使用JAMAR测量。测功机和功能能力通过Timed Up and Go（TUG）测试。进行血液测试并评估血清C反应蛋白和白介素6水平。 Spearman系数用于分析变量与Mann-Whitney之间的相关性以进行组间比较。显着性设定为0.05。结果：GS，TUG和炎性介质（CRP和IL-6）之间没有显着相关性。但是，通过调整年龄，性别和肌肉质量等变量，可以发现GS和CPR之间存在显着的负相关关系（p = 0.023）。结论：C反应蛋白水平低的老年人在握力测试中表现更好。重要的是研究衰老过程中老年人中炎性细胞因子可能对功能能力产生的不利影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号