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Polyunsaturated fatty acids, inflammation, and metabolic syndrome in South Asian Americans in Maryland

机译：马里兰南亚裔美国人的多不饱和脂肪酸，炎症和代谢综合症

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Metabolic syndrome (MetS) is characterized by the accumulation of cardiovascular risk factors among men and women worldwide. The use of very long‐chain polyunsaturated fatty acids (VLC PUFA) could potentially benefit individuals with MetS. The goal was to better understand the relationship between MetS and VLC PUFA in South Asian (SA) Americans who experience an elevated risk for heart disease. We analyzed a cross section of South Asian (SA) using the automated self‐administered 24‐hr recall (ASA24) and clinic data in a low‐income SA in Maryland. We found no correlation between MetS indicators (high‐density lipoprotein (HDL) cholesterol, triglycerides, fasting blood glucose, diastolic blood pressure, and waist circumference (WC)) and dietary n‐3 PUFA (eicosapentaenoic, docosapentaenoic acids). However, dietary n‐6 VLC PUFA (arachidonic acid [AA]) was associated with cholesterol and fasting blood glucose levels. SA with MetS did not have a significantly low level of dietary VLC PUFA intake, and there were no SA group differences in the intake of VLC PUFA but there were significant gender differences. Dietary practices in SA may contribute to increased proinflammatory markers and play a role in elevated MetS components.
机译：代谢综合症（MetS）的特征是全世界男性和女性中心血管危险因素的累积。使用超长链多不饱和脂肪酸（VLC PUFA）可能会使患有MetS的患者受益。目的是更好地了解患有心脏病风险较高的南亚（SA）美国人中MetS与VLC PUFA之间的关系。我们使用自动自我管理的24小时召回（ASA24）和马里兰州低收入SA的临床数据分析了南亚（SA）的横截面。我们发现MetS指标（高密度脂蛋白（HDL）胆固醇，甘油三酸酯，空腹血糖，舒张压和腰围（WC））与膳食n-3 PUFA（二十碳五烯酸，二十二碳五烯酸）之间没有相关性。但是，饮食中的n-6 VLC PUFA（花生四烯酸[AA]）与胆固醇和空腹血糖水平有关。具有MetS的SA饮食中VLC PUFA的摄入量没有明显降低，并且VLC PUFA的摄入中SA组没有差异，但是性别存在显着差异。 SA中的饮食习惯可能有助于增加促炎性标志物，并在MetS组分升高中发挥作用。

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