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首页> 外文期刊>Macedonian Academy of Sciences and Arts: Section of Biological and Medical Sciences >EFFECT OF ADDING DEXAMETHASONE AS A ROPIVACAINE ADJUVANT IN ULTRASOUND-GUIDED TRANSVERSUS ABDOMINIS PLANE BLOCK FOR INGUINAL HERNIA REPAIR
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EFFECT OF ADDING DEXAMETHASONE AS A ROPIVACAINE ADJUVANT IN ULTRASOUND-GUIDED TRANSVERSUS ABDOMINIS PLANE BLOCK FOR INGUINAL HERNIA REPAIR

机译:添加地塞米松作为罗哌卡因的佐剂在超声引导的横贯腹肌平面阻滞术中对腹股沟疝的修复作用

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Background: The transverses abdominals plane block (TAP) is a regional anesthesia technique that provided analgesia to the parietal peritoneum, skin and muscles of the anterior abdominal wall. The aim of this randomized double-blind study was to evaluate postoperative analgesia on patients undergoing open inguinal hernia repair under general anesthesia (GA), (GA + TAP) block preformed with ropivacaine and (GA + TAP-D) block preformed with ropivacaine and 4 mg dexamethasone. Methods: 90 (ASA I–II) adult patients for unilateral open inguinal hernia repair were included in this study. In group I (n = 30) patents received only general anesthesia (GA). Patients in group II (n = 30) received GA and unilateral TAP block with 25 ml of 0.5% ropivacaine and the patients in group III (n = 30) received GA and unilateral TAP-D block with 25 ml of 0.5% ropivacaine + 4 mg Dexa- methadsone. In this study we assessed the pain score – VAS at rest at 2, 4, 6, 12 and 24 hours after the operation and the total analgesic consumption of morphine over 24 hours. Results: There were statistically significant differences in the VAS scores between group I, group II and group III at all postoperative time points – 2 hr , 4 hr , 6 hr , 12 hr and 24 hr. (p 0.00001). The cumulative 24 hours morphine consumption after the operation was significantly lower in group III (5.53 1.21 mg) than in group II (6.16 2.41 mg) and group I (9.26 2.41 mg). This difference is statistically significant (p 0.00001). Conclusion: Concerning the inguinal hernia repair we found better postoperative pain scores and 24 hours reduction of the morphine consumption in group III (GA and TAP-D block ) compared with group I (GA) and group II (GA + TAP block).
机译:背景:腹横肌平面阻滞(TAP)是一种局部麻醉技术,可为腹膜前壁,前腹壁的皮肤和肌肉提供镇痛作用。这项随机双盲研究的目的是评估在全身麻醉(GA),罗哌卡因预制的(GA + TAP)阻滞和罗哌卡因预制的(GA + TAP-D)阻滞下接受开放性腹股沟疝修补术的患者的术后镇痛效果。 4毫克地塞米松。方法:本研究包括90例单侧开放性腹股沟疝修补术的成年患者(ASA I–II)。在第一组(n = 30)中,专利仅接受全身麻醉(GA)。 II组(n = 30)的患者接受GA和单侧TAP阻滞剂加25 ml 0.5%罗哌卡因,III组(n = 30)的患者接受GA和单侧TAP-D阻滞剂加25 ml 0.5%罗哌卡因+ 4毫克地塞美沙酮。在这项研究中,我们评估了疼痛评分–术后2、4、6、12和24小时休息时的VAS以及24小时内吗啡的总镇痛消耗量。结果:在所有术后时间点– 2小时,4小时,6小时,12小时和24小时,I组,II组和III组之间的​​VAS评分存在统计学差异。 (p <0.00001)。 Ⅲ组(5.53 1.21 mg)术后24小时累计吗啡消耗量显着低于Ⅱ组(6.16 2.41 mg)和Ⅰ组(9.26 2.41 mg)。这种差异具有统计学意义(p <0.00001)。结论:关于腹股沟疝修补术,我们发现与I组(GA)和II组(GA + TAP阻滞)相比,III组(GA和TAP-D阻滞)的术后疼痛评分更高,吗啡消耗量减少了24小时。

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