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The Neural Association between Tendency to Forgive and Spontaneous Brain Activity in Healthy Young Adults

机译:健康年轻人的原谅和自发性大脑活动倾向之间的神经关联

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The tendency to forgive (TTF) refers to one’s global dispositional level of forgiveness across situations and relationships. Previous brain imaging studies examined activation patterns underlying forgiving process, yet the association between individual differences in the TTF and spontaneous brain activity at resting-state remains unknown. In this study, resting-state functional magnetic resonance imaging (fMRI) was used to investigate the correlation between the TTF and spontaneous brain activity in a young adult sample. Participants were 178 young students (55 men) who completed the TTF scale and underwent a resting-state fMRI scan. Multiple regression analysis was conducted to assess the association between the regional amplitude of low-frequency fluctuations (ALFF) and TTF scores corrected for age and sex. Results showed that the ALFF value in the right dorsomedial prefrontal cortex (dmPFC), precuneus and inferior parietal lobule (IPL) were negatively associated with TTF scores. These findings suggest that the spontaneous brain activity of brain regions like the dmPFC, precuneus and IPL which are implicated in mentalizing and empathic response are associated with individual differences in the TTF.
机译:宽恕趋势(TTF)是指某人在各种情况和关系中对宽恕的全球性倾向。先前的脑成像研究检查了宽恕过程背后的激活模式,但是在TTF个体差异与静止状态下自发性脑活动之间的关联仍然未知。在这项研究中,静止状态功能磁共振成像(fMRI)用于研究年轻成年人样本中TTF与自发性大脑活动之间的相关性。参加者为178名年轻学生(55名男性),他们完成了TTF量表并接受了静息状态fMRI扫描。进行了多元回归分析,以评估低频波动(ALFF)的区域幅度与针对年龄和性别校正的TTF得分之间的关​​联。结果显示,右背背前额叶皮层(dmPFC),早孕和顶下小叶(IPL)的ALFF值与TTF评分呈负相关。这些发现表明,与dTFPFC,早产儿和IPL有关的大脑区域的自发性大脑活动与思维能力和移情反应有关。

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