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首页> 外文期刊>Medical science monitor : >Evaluation of prostate specific antigen (t-PSA and f-PSA) in blood serum in screening research on prostate cancer
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Evaluation of prostate specific antigen (t-PSA and f-PSA) in blood serum in screening research on prostate cancer

机译：血清前列腺特异性抗原（t-PSA和f-PSA）在前列腺癌筛查研究中的价值

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The objective of this research was to evaluate how useful the estimation of PSA (total (t-PSA) and free (f-PSA) fractions) concentration in blood serum can be in screening prostate cancer in men who were not previously examined by a urologist. TPSA and fPSA concentrations were estimated in 444 volunteers at the 38-85 age range. Men (n=76) with tPSA concentrations in 'grey zone' and above were offered further urologic examination. Sextant method prostate biopsy was performed in 45 cases. 368 volunteers (83%) had tPSA concentration within physiological range, 51 volunteers (11.5%) had tPSA concentration in 'grey zone' and 25 volunteers (5.5%) had tPSA concentration above 10 ng/ml. 7 cases of prostate cancer were found. Expected percentage of detectability of prostate cancer in the population was 2.7%.
机译：这项研究的目的是评估血清PSA（总（t-PSA）和游离（f-PSA）分数）的浓度对筛查未曾由泌尿科医师检查过的男性前列腺癌的有用性。 。估计444名38-85岁年龄段志愿者中的TPSA和fPSA浓度。男性（n = 76）的tPSA浓度在“灰色区”及以上的男性，接受了进一步的泌尿科检查。在45例中进行了六种方法的前列腺活检。 368名志愿者（83％）的tPSA浓度在生理范围内，51名志愿者（11.5％）的tPSA浓度在“灰色区”，25名志愿者（5.5％）的tPSA浓度高于10 ng / ml。发现前列腺癌7例。人群中前列腺癌可检测性的预期百分比为2.7％。

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