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Effects of hydrogen-rich water bath on visceral fat and skin blotch, with boiling-resistant hydrogen bubbles

机译：富氢水浴对内脏脂肪和皮肤斑点的影响，具有耐沸腾的氢气泡

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Hydrogen-dissolved water has been shown to improve diverse oxidation stress-related diseases, which drove us to examine effects of hydrogen-rich water on oxidation stress-related skin troubles and lipid-metabolism markers. The purpose of this study is whether the dissolved hydrogen in hydrogen-rich water was kept even after boiling, and whether hydrogen-bath utilization improves cosmetic effects such as skin-blotch repression and the visceral-fat-based slimming effects. The subjects were two men and two women, aged 48, 43, 42, and 41 years (n = 4). They took warm (41°C) water bath of dissolved hydrogen 300–310 μg/L ( 10 μg/L for normal water) for 10-minute once daily for 1–6 months, followed by examination of skin blotch, visceral fat, and cholesterol and glucose metabolisms. The dissolved hydrogen concentration was measured after 15-minute boiling and the subsequent cooling naturally. The wide-ranging, dense, and irregularly shaped skin blotches became markedly smaller and thinner, assumedly through reductive bleaching of melanin and lipofuscin and promotion of dermal cell renewal by the hydrogen-rich warm water. Ultrasonic resonance-based analysis on the abdominal cross-section revealed that the visceral fat area decreased from 47 to 36 cmsup[2]/sup, and the abdominal circumference decreased from 91 to 82 cm, in the two female subjects bathing in hydrogen-water. After 6-month hydrogen-water bathing, the low-density lipoprotein cholesterol level was decreased by 16.2% and the fasting blood glucose level increased by 13.6% in the blood of a female subject. Before boiling, the dissolved hydrogen and an oxidation-reduced potential were 300 μg/L and –115 mV, respectively. Dissolved hydrogen was retained at 300–175 μg/L and 200 μg/L, even 1–6 hours and 24 hours, respectively, after boiling. Therefore, a hydrogen-rich water-bath apparatus can electrolytically generate abundant boiling-resistant hydrogen bubbles, improving visceral fat and blotches on the skin. The study was approved by the Medical Ethics Committee of the Japanese Center for Anti-Aging Medical Sciences and that was officially authenticated by the Hiroshima Prefecture Government of Japan (approval number 15C1) in 2016.
机译：氢溶解的水已被证明可以改善多种与氧化应激有关的疾病，这驱使我们研究富氢水对氧化应激相关的皮肤疾病和脂质代谢标志物的影响。这项研究的目的是在沸腾后是否仍保留富氢水中的溶解氢，以及利用氢浴是否可以改善美容效果，例如抑制皮肤色斑和基于内脏脂肪的减肥效果。受试者为两男两女，分别为48岁，43岁，42岁和41岁（n = 4）。他们每天用温水（41°C）的溶解氢300-310μg/ L（对于普通水<10μg/ L）每天洗10分钟，持续1-6个月，然后检查皮肤斑点，内脏脂肪以及胆固醇和葡萄糖代谢。煮沸15分钟后自然冷却，然后测量溶解的氢浓度。广泛的，致密的和不规则形状的皮肤斑点变得明显更小，更薄，这可能是由于黑色素和脂褐素的还原性漂白以及富含氢的温水促进了真皮细胞的更新。基于超声的腹部横截面分析显示，两名女性受试者的内脏脂肪面积从47 cm [2] 减少，腹围从91 cm减少至82 cm沐浴在氢水中。经过6个月的氢水沐浴后，女性受试者的血液中低密度脂蛋白胆固醇水平降低了16.2％，空腹血糖水平升高了13.6％。沸腾前，溶解氢和氧化还原电位分别为300μg/ L和–115 mV。煮沸后，即使在1-6小时和24小时，溶解的氢气也分别保持在300-175μg/ L和200μg/ L。因此，富氢水浴装置可以电解产生大量的耐沸腾氢气泡，改善内脏脂肪和皮肤上的斑点。该研究已获得日本抗衰老医学科学中心医学伦理委员会的批准，并于2016年由日本广岛县政府正式批准（批准号15C1）。

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