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首页> 外文期刊>Korean Circulation Journal >Angiographic Differences Analysis of Coronary Artery Lesions in Patients with Stable and Unstable Angina Pectoris
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Angiographic Differences Analysis of Coronary Artery Lesions in Patients with Stable and Unstable Angina Pectoris

机译:稳定和不稳定型心绞痛患者冠状动脉病变的血管造影差异分析

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Background and Objectives As previously reported, unstable angina is usually related to characteristic coronary artery lesion's morphology analyzed by coronary angiogram. This takes the form of an eccentrically placed convex stenosis with a narrow neck due to one or more overhanging edges or irregular, scalloped borders, or both. Although most studies were done for lesions with high degree stenosis(>50%), recent studies emphasized the role of vulnerability of plaque in acute coronary syndrome and even mild degree stenotic lesions may progress rapidly to evoke acute coronary syndrome. Therefore in this study, we analyzed the morphological characteristics of coronary artery lesions with mild degree stenosis as well as severe stenosis. Materials and Method We conducted a retrospective study of 96 patients with angina pectoris (42 of stable patients and 54 of unstable patients) who underwent coronary angiography. Each lesions with 25% or greater diameter stenosis were categorized into simple and complex lesion(convex intraluminal obstruction with a narrow neck or irregular borders, diffuse irregularities, ulceration, thrombus). Calcification of coronary artery, extents of lesions were analyzed and stenosis grade and location were categorized by AHA classification. Results There were no significant differences between the stable angina and unstable angina in risk factors and vessel involvement, numbers of lesions, calcification and total obstruction. In morphologic analysis, complex lesions were more frequent in unstable angina than stable angina (49% vs 33%, p Conclusions The lesions with both complex morphology and severe degree stenosis are closely implicated in unstable angina.
机译:背景与目的如先前报道,不稳定型心绞痛通常与通过冠状动脉造影分析的特征性冠状动脉病变的形态有关。由于一个或多个外伸边缘或不规则的扇贝形边框,或两者兼而有之,因此偏心放置狭窄颈部的凸状狭窄。尽管大多数研究针对高度狭窄(> 50%)的病变,但最近的研究强调斑块易损性在急性冠状动脉综合征中的作用,即使轻度狭窄的病变也可能迅速发展为诱发急性冠状动脉综合征。因此,在本研究中,我们分析了轻度狭窄和重度狭窄的冠状动脉病变的形态特征。材料和方法我们对96例接受冠状动脉造影的心绞痛患者(42例稳定患者和54例不稳定患者)进行了回顾性研究。将直径狭窄程度大于或等于25%的每个病变分为简单病变和复杂病变(管腔狭窄,颈部狭窄或边界不规则,弥漫性不规则,溃疡,血栓)。分析冠状动脉钙化,病变程度,并通过AHA分类对狭窄程度和位置进行分类。结果稳定型心绞痛和不稳定型心绞痛的危险因素,血管受累,病变数目,钙化和总梗阻均无明显差异。在形态学分析中,不稳定型心绞痛的复杂病变比稳定型心绞痛的发病率更高(49%vs 33%,p结论)形态复杂且严重程度狭窄的病变与不稳定型心绞痛密切相关。

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