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Semiconductor quantum dots as fluorescent probes for in vitro and in vivo bio-molecular and cellular imaging

机译：半导体量子点作为用于体外和体内生物分子和细胞成像的荧光探针

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摘要

Over the years, biological imaging has seen many advances, allowing scientists to unfold many of the mysteries surrounding biological processes. The ideal imaging resolution would be in nanometres, as most biological processes occur at this scale. Nanotechnology has made this possible with functionalised nanoparticles that can bind to specific targets and trace processes at the cellular and molecular level. Quantum dots (QDs) or semiconductor nanocrystals are luminescent particles that have the potential to be the next generation fluorophores. This paper is an overview of the basics of QDs and their role as fluorescent probes for various biological imaging applications. Their potential clinical applications and the limitations that need to be overcome have also been discussed.
机译：多年来，生物成像技术取得了许多进步，使科学家们得以揭示生物过程中的许多谜团。理想的成像分辨率应在纳米级，因为大多数生物过程都在此规模上发生。纳米技术通过功能化的纳米颗粒使之成为可能，该纳米颗粒可以结合特定的靶标并在细胞和分子水平上追踪过程。量子点（QD）或半导体纳米晶体是发光粒子，具有成为下一代荧光团的潜力。本文概述了量子点的基本原理及其在各种生物成像应用中作为荧光探针的作用。还讨论了它们的潜在临床应用和需要克服的局限性。

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