首页> 外文期刊>Nepal Journal of Epidemiology >Estimation of the burden of people living with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) in Kerala state, India
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Estimation of the burden of people living with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) in Kerala state, India

机译:估计印度喀拉拉邦患有人类免疫缺陷病毒/后天免疫缺陷综合症(HIV / AIDS)的人的负担

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Background: Worldwide, 36.7 million people were infected with Acquired Immunodeficiency Syndrome (AIDS) by the end of 2015. Over the period 2007 to 2015, there was a declining trend in the prevalence of adult Human Immunodeficiency Virus (HIV) in the state of Kerala, India. The current study aims to find a suitable statistical modelling technique for the distribution of HIV incubation time and predict the cumulative number of AIDS cases. Materials and Methods: The requisite data were obtained from the Kerala State AIDS Control Society (KSACS) for the years 2007 to 2015. To assess the distribution of HIV incubation time, the data of 22 HIV-infected Keralite patients were retrieved from the medical records of a teaching hospital. Data included age, gender, and incubation time. The back-calculation method was utilized to predict the cumulative HIV/AIDS cases. Results: The estimated total cumulative AIDS cases in Kerala for the years 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014 and 2015 were found to be 35,777, 48,944, 62,039, 45,669, 45,668, and 43,605, 42,377, 39,362, 37,617, 39,583, 25,414 respectively using back-calculation method with Weibull (2) incubation time distribution. The mean incubation time of the total HIV cases (male and female) was 4.4 years which indicates a rapid progression of the disease in the state of Kerala. Conclusion: The back-calculation method is a powerful tool to estimate the cumulative frequency of AIDS cases; which predicted a declining HIV trend among Keralites. Moreover, the Weibull distribution is the best fitted distribution for HIV incubation time in our population.
机译:背景:到2015年底,全球共有3670万人感染了获得性免疫缺陷综合症(AIDS)。在2007年至2015年期间,喀拉拉邦的成人人类免疫缺陷病毒(HIV)流行率呈下降趋势,印度。当前的研究旨在找到一种合适的统计模型技术,用于艾滋病毒潜伏时间的分布并预测艾滋病病例的累积数量。资料和方法:从喀拉拉邦艾滋病控制协会(KSACS)获得2007年至2015年的必要数据。为评估HIV潜伏期的分布,从医疗记录中检索了22名感染HIV的Keralite患者的数据。教学医院。数据包括年龄,性别和潜伏时间。利用反算方法预测了艾滋病毒/艾滋病的累积病例。结果:发现喀拉拉邦2005年,2006年,2007年,2008年,2009年,2010年,2011年,2012年,2013年,2014年和2015年的累计AIDS病例总数估计为35,777、48,944、62,039、45,669、45,668和43,605使用Weibull(2)孵育时间分布的反算方法分别对42,377、39,362、37,617、39,583、25,414进行了分析。所有艾滋病毒病例(男性和女性)的平均潜伏时间为4.4年,这表明该疾病在喀拉拉邦迅速发展。结论:反算方法是估算艾滋病病例累积频率的有力工具。这预示着Keralites中的HIV趋势将下降。而且,Weibull分布是我们人群中HIV潜伏时间的最佳拟合分布。

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