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首页> 外文期刊>Leukemia Research and Treatment >Postinduction Supportive Care of Pediatric Acute Myelocytic Leukemia: Should Patients be Kept in the Hospital?
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Postinduction Supportive Care of Pediatric Acute Myelocytic Leukemia: Should Patients be Kept in the Hospital?

机译：小儿急性粒细胞白血病的诱导后支持治疗：患者应该住院吗？

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Children with AML become profoundly neutropenic while they undergo remission induction chemotherapy. It is unknown whether these children should be kept in the hospital while they are severely neutropenic to prevent life-threatening complications associated with neutropenia and reduce fatality. We at our institution routinely discharge patients after completing remission induction chemotherapy in the presence of profound neutropenia, unless it is clinically contraindicated. We reviewed all AML patients who were consecutively treated at our hospital from 1989 to 2011. Thirteen patients were electively discharged after completion of induction I chemotherapy. Of the 13, 4 died due to relapse or complications of stem cell transplants (not due to neutropenia related complications). Another eight are long term survivors. In this very small series, discharge from the hospital even though patients were severely neutropenic did not adversely affect the survival.
机译：AML儿童在接受缓解诱导化学疗法时会严重中性粒细胞减少。尚不清楚这些儿童严重中性粒细胞减少时是否应该留在医院，以防止与中性粒细胞减少有关的危及生命的并发症并减少死亡。除非有临床禁忌症，否则在严重中性粒细胞减少的情况下，完成缓解诱导化疗后，我们所在机构将常规出院患者。我们回顾了从1989年至2011年在我们医院接受连续治疗的所有AML患者。完成诱导I化疗后，有13例患者选择出院。在13例中，有4例死于干细胞移植的复发或并发症（不是由于中性粒细胞减少症相关的并发症）。另外八个是长期幸存者。在这个非常小的系列中，即使患者严重中性粒细胞减少，出院也不会对生存产生不利影响。

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