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首页> 外文期刊>Research Journal of Medical Sciences >The Effect of Highly Active Antiretroviral Therapy on CD4 Counts and Body Weight in HIV/AIDS Patients in South West Nigeria
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The Effect of Highly Active Antiretroviral Therapy on CD4 Counts and Body Weight in HIV/AIDS Patients in South West Nigeria

机译：高效抗逆转录病毒疗法对尼日利亚西南部HIV / AIDS患者CD4计数和体重的影响

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Prior to the advent of HAART the diagnosis of HIV/AIDS was a death sentence. Research has shown that this is no more the case. This retrospective study was aimed at determining the effect of HAART on CD4 counts and body weight of HIV-positive subjects. The CD4 counts and body weight of HIV-positive patients were accessed from the records of HIV clinic of LAUTECH Teaching Hospital, Oshogbo. The data comprised of records of the CD4 counts and body weight of fifty HIV-positive patients not on HAART treatment and that of fifty HIV-positive patients on HAART treatment for a period of 1 year. Results showed a significant difference between mean CD4 counts of control subjects and test subjects (p<0.05). This significant difference represents an increase in CD4 count of HIV patients on HAART. This study also shows no significant difference between mean body weight of control subjects and test subjects (p>0.05). This study highlights the need for importance of regular monitoring of the CD4 count and body weight in HIV patients in order to determine when to start treatment with HAART therapy to prevent the invasion of life threatening opportunistic infections.
机译：在HAART出现之前，对HIV / AIDS的诊断是死刑。研究表明，情况不再如此。这项回顾性研究旨在确定HAART对HIV阳性受试者CD4计数和体重的影响。从Oshogbo LAUTECH教学医院的HIV诊所记录中获取HIV阳性患者的CD4计数和体重。该数据包括50名未接受HAART治疗的HIV阳性患者和50名接受HAART治疗1年的HIV阳性患者的CD4计数和体重的记录。结果显示，对照受试者和测试受试者的平均CD4计数之间存在显着差异（p <0.05）。这种显着差异表示在HAART上HIV患者的CD4计数增加。这项研究还显示，对照受试者和测试受试者的平均体重之间没有显着差异（p> 0.05）。这项研究强调了定期监测HIV患者CD4计数和体重的重要性，以便确定何时开始使用HAART治疗以防止危及生命的机会性感染的开始。

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