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首页> 外文期刊>Reumatologia >Changes in body composition and bone mineral density n postmenopausal women with psoriatic arthritis
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Changes in body composition and bone mineral density n postmenopausal women with psoriatic arthritis

机译：绝经后牛皮癣关节炎妇女的身体成分和骨矿物质密度的变化

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Objective : Prolonged inflammation status due to psoriatic arthritis (PsA) may contribute to the loss of muscle mass, extending from muscle weakness, and increased risk of falls and fractures. The risk of fractures and their complications increases with concomitant osteoporosis. Material and methods : The study included 95 women aged 50–75 years. The presence of sarcopenia was evaluated in a group of 51 women with PsA, and 44 controls (without inflammatory joint disease). Measurements of muscle mass and lean body mass were made using the method of bioimpedance assessing ALM (Appendicular Lean Mass) index and SMI (Skeletal Muscle Index). The diagnosis of sarcopenia was made in women with low muscle mass and concomitant reduction of the efficiency of the assessed functional test Timed Up and Go (TUG). Bone density measurement was done by densitometry in the femoral neck and lumbar spine. (Ethics statement OIL 625/16/Bioet). Results : Sarcopenia, using ALM index and SMI, was diagnosed in 13.7% and 43.1% of PsA women, and in healthy women in 9% and 20.4%, respectively. In the group of PsA, sarcopenia was associated with a significant increase in the occurrence of disorders of bone mineralisation (72.7% vs. 41.3% in patients without a decrease in muscle mass). There was no correlation between the loss of muscle mass, bone density, and activity of PsA. Conclusions : The prevalence of sarcopenia in postmenopausal women suffering from PsA is associated with the occurrence of osteoporosis.
机译：目的：由于银屑病关节炎（PsA）引起的长时间炎症状态可能会导致肌肉质量的丧失，由肌肉无力引起，并增加跌倒和骨折的风险。伴随骨质疏松而增加骨折和并发症的风险。材料和方法：该研究纳入了95位年龄在50-75岁之间的女性。在一组51名患有PsA的女性和44名对照组（无炎性关节疾病）中评估了少肌症的存在。肌肉质量和瘦体重的测量使用生物阻抗评估ALM（附录瘦体重）指数和SMI（骨骼肌指数）的方法进行。肌肉减少症的诊断是在肌肉质量低下，同时进行的功能测试时间和运动时间（TUG）降低的女性中进行的。骨密度的测量是通过股骨颈和腰椎的密度测定法进行的。 （道德声明OIL 625/16 / Bioet）。结果：使用ALM指数和SMI诊断的骨肉减少症的PsA女性的诊断率为13.7％和43.1％，健康女性的诊断为9％和20.4％。在PsA组中，肌肉减少症与骨矿化疾病的发生率显着增加有关（72.7％，而肌肉量没有减少的患者为41.3％）。肌肉质量的丧失，骨密度与PsA活性之间没有相关性。结论：绝经后女性患有PsA的肌肉减少症的患病率与骨质疏松的发生有关。

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