首页> 外文期刊>Revista Cubana de Hematología, Inmunología y Hemoterapia >Prevalencia y significado cl?-nico de los anticuerpos anti-SS-A(RO) en pacientes con enfermedades reum??ticas autoinmunes sist??micas
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Prevalencia y significado cl?-nico de los anticuerpos anti-SS-A(RO) en pacientes con enfermedades reum??ticas autoinmunes sist??micas

机译:系统性自身免疫性风湿病患者中抗SS-A(RO)抗体的患病率及其临床意义

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Due to the diagnostic importance of the detection of different antibody specificities that allows us to distinguish rheumatic syndromes that clinically overlap; we studied its prevalence in a group of 4 693 patients with systemic autoimmune rheumatic diseases In the period between June 10, 2010 and June 10, 2016. For that purpose we used ANA Screen and ANA Combi. 277 (5 %) were female and 250 male. There was a significant prevalence of anti-SS-A antibodies140 (50 %) followed by antinucleosome 97 (35 %) and DNAs of 72 (25 %), no significant results were obtained with the rest of the other antibodies. Our results suggest the usefulness of these tests in patients with clinical manifestations of systemic autoimmune rheumatic diseases together with the clinical and histological information that could help to make an accurate diagnosis.
机译:由于检测不同抗体特异性的诊断重要性,这使我们能够区分临床上重叠的风湿性综合征;我们在2010年6月10日至2016年6月10日期间的4 693例系统性自身免疫性风湿性疾病患者中研究了其患病率。为此,我们使用了ANA Screen和ANA Combi。女性277位(5%),男性250位。抗SS-A抗体140(50%)的患病率很高,其次是抗核小体97(35%)和DNA的72(25%),其余的其他抗体未获得明显的结果。我们的结果表明,这些检查对系统性自身免疫性风湿性疾病临床表现的患者有用,以及有助于做出准确诊断的临床和组织学信息。

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